杏灵分散片联合甲钴胺与单用甲钴胺治疗糖尿病周围神经病变的对照研究  

A Comparative Study of Xingling Tablet Combined Methylcobalamin Therapy and Single Methylcobalamin Therapy in the Treatment of Diabetic Peripheral Neuropathy

作　　者：高洁[1] 杜燕[1] 杨晓平[1] 

机构地区：[1]四川省宜宾市第一人民医院神经内科,644000

出　　处：《临床合理用药杂志》2011年第10X期5-6,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察杏灵分散片联合甲钴胺与单用甲钴胺治疗糖尿病周围神经病变的疗效。方法将50例糖尿病周围神经病变患者随机分为杏灵分散片联合甲钴胺治疗组(研究组,25例)和单用甲钴胺治疗组(对照组,25例),分别在治疗前、治疗后行神经传导速度测定以评估疗效。结果研究组总有效率为88%,与对照组总有效率(76%)比较,差异有统计学意义(P<0.05)。结论杏灵分散片联合甲钴胺治疗糖尿病周围神经病变时疗效明显优于甲钴胺单一治疗,临床医生可以更多地考虑选用该联合用药方案。Objective To compare the efficacy between XingLing tablet combined methlcobalamin therapy and single methlcobalamin therapy in the treatment of diabetic peripheral neuropathy.Methods 50 patients with diabetic peripheral neuropathy were random divided into group of XingLing tablet combined methlcobalamin therapy （research group） and single methlcobalamin therapy （control group）.The clinical efficacy were assessed by nerve conductive velocity for two times （before therapy,on fourth weekend）.Results Comparing the research group to the controlled group the effect was obviously better on fourth weekend（P〈0.05）.Conclusion The clinicians may choose the effective XingLing tablet combined methlcobalamin therapy as a way of treating diabetic peripheral neuropathy.

关 键 词：糖尿病神经病变 杏灵分散片 甲钴胺 

分 类 号：R587.2[医药卫生—内分泌]