大疱性皮肤病53例免疫荧光和组织病理检查结果分析  

Analysis of Immunofluorescence and Histopathologic Examination on 53 Cases of Bullous Diseases

作　　者：张东红[1] 韦海明[2] 黄琦涛[1] 李玉秋[1] 

机构地区：[1]广西壮族自治区人民医院皮肤性病科,广西南宁530021 [2]广西壮族自治区人民医院病理科,广西南宁530021

出　　处：《中国皮肤性病学杂志》2011年第12期944-945,948,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨直接免疫荧光(DIF)和盐裂皮肤DIF技术在诊断大疱性皮肤病中的价值。方法采用DIF和盐裂皮肤DIF技术检测53例大疱性皮肤病标本,并与其组织病理检查结果进行比较。结果 DIF和盐裂皮肤DIF技术诊断该类疾病的阳性率(90.57%)显著高于对其进行组织病理检查的阳性率(73.58%),差异有统计学意义(P<0.05)。结论 DIF和盐裂皮肤DIF技术仍是目前诊断和鉴别诊断大疱性皮肤病的可靠方法。Objective To explore the diagnostic valuation of direct immunofluorescence and sodium chloride-separated skin direct immunofluorescence in bullous diseases. Methods Fifty-three cases of bullous diseases were detected by direct immunofluorescence and sodium chloride-separated skin direct immunofluorescence, and compared with histopathologic examination. Results The diagnostic rate of DIF and sodium chloride-separated skin DIF was significantly higher than that of histopathologic examination （90.57% vs 73.58% , P 〈0.05）. Conclusion At present, DIF and sodium chloride-separated skin DIF is still a more reliable technique for the diagnosis and differentiation of bullous diseases.

关 键 词：直接免疫荧光 盐裂皮肤DIF 组织病理 大疱性皮肤病 

分 类 号：R758.66[医药卫生—皮肤病学与性病学]