基于联萘酚的手性冠醚的合成及其晶体结构  

Synthesis of chiral crown ethers based on binaphthol and their crystal structure

作　　者：焦书燕[1] 姚文涌[1] 谢恩[1] 徐括喜[1] 

机构地区：[1]河南大学化学化工学院,河南开封475004

出　　处：《化学研究》2011年第6期1-4,共4页Chemical Research

基　　金：国家自然科学基金项目(20872027/B0206);河南省教育厅基金项目(2010B150004)

摘　　要：以R-或S-联萘酚、2,2′-联苯酚、间苯二酚、氯腈胺为原料合成了六个手性冠醚,所得冠醚的结构均经元素分析、质谱、红外光谱以及核磁共振氢谱和碳谱验证;并利用X射线衍射分析确定了单晶R-3的晶体结构.结果表明,合成产物属于单斜晶系,P2(1)/n空间群,晶胞参数为:a=1.181 8(2)nm,b=0.794 38(15)nm,c=1.488 9(3)nm,β=94.263°,Z=2,Dc=1.490g.cm-3,F(000)=644.Six chiral crown ethers were synthesized with R-or S-binaphthol,2,2′-biphenol,resorcinol,and cyanoamine chloride as starting materials.As-synthesized compounds were characterized by means of elemental analysis,mass spectrometry（MS）,infrared spectrometry,and nuclear magnetic resonance spectroscopy（1H and 13C NMR）.Moreover,the crystal structure of single crystal R-3 was determined based on X-ray diffraction analysis.Results show that as-synthesized compound belongs to monoclinic system of P2（1）/n space group,with cell parameters being a = 1.181 8（2） nm,b = 0.794 38（15） nm,c = 1.488 9（3） nm,β = 94.263°,Z = 2,Dc = 1.490 g/cm-3,and F（000）= 644.

关 键 词：联萘酚 手性冠醚 晶体结构 

分 类 号：O641.4[理学—物理化学]