缩水甘油基叔基丁基醚的合成  

Synthesis of tert-Butyl Glycidyl Ether

作　　者：张雨青[1] 蔡照胜[1] 

机构地区：[1]盐城工学院化学与生物工程学院,江苏盐城224003

出　　处：《化学世界》2011年第11期684-686,共3页Chemical World

基　　金：国家"948"成果转化项目(2009-04-55);应用化学省重点科建设开放基金项目(XKY2009005)

摘　　要：以环氧氯丙烷和叔丁醇为基本原料,经加成反应和环化作用,合成了缩水甘油基叔丁基醚(TBGE);用正交实验方法优化了TBGE的合成条件,气相色谱法分析了产品中TBGE含量,GC-MS和FT-IR等表征了产物结构。结果表明,在以BF3-乙醚为催化剂时,合成TBGE的适宜条件为:加成反应的温度和时间分别为50.0℃和5.0 h,n(环氧氯丙烷)/n(叔丁醇)为2.5,BF3-乙醚的用量为叔丁醇质量的3.0%;在此条件下,TBGE的收率为85.72%。The tert-butyl glycidyl ether（TBGE） was synthesized through additive reaction and cyclic action with epichlorohydrin and tert-butanol as raw material.The synthetic conditions were optimized using orthogonal experiment method,The content of TBGE in product was determined by GC and the structure of product was characterized by GC-MS and FT-IR.When BF3-etherate was utilized as catalyst,the optimum conditions for the synthesis of TBGE were as follows： the temperature of additive reaction was 50.0 ℃,the reaction time was 5.0 h,the molar ratio of epichlorohydrin versus tert-butanol was 2.5 and the mass ratio of BF3-etherate versus tert-butanol was 3.0%.Under these conditions,the yield of TBGE was 85.72%.

关 键 词：缩水甘油基叔丁基醚 加成反应 环化作用 条件优化 

分 类 号：O621.3[理学—有机化学]