血清胱抑素C和尿微量白蛋白在慢性肾小球肾炎早期肾功能损害评估中的意义  

The significance of the serum Cystatin C and uric microalbumin in evaluating the early renal impairment of the patients with chronic glomerulonephritis

作　　者：周碧燕[1] 李友邕[1] 钟德斌[1] 覃政[1] 文延峰[1] 

机构地区：[1]南宁市第一人民医院检验科,广西南宁530022

出　　处：《中国医药导报》2011年第34期95-96,共2页China Medical Herald

摘　　要：目的:探讨血清胱抑素C(Cys C)和24 h尿微量白蛋白(24 h U-mAlb)在慢性肾小球肾炎早期肾功能损害评估中的临床意义。方法:检测43例慢性肾小球肾炎早期肾功能损害患者(观察组)血清Cys C和24 h U-mAlb水平,并与43例健康体检者(正常对照组)进行对照分析。结果:慢性肾小球肾炎早期肾功能损害患者血清Cys C、24 h U-mAlb明显高于正常对照组(P<0.05);慢性肾小球肾炎早期肾功能损害患者血清Cys C和24 h U-mAlb检出率比较,差异无统计学意义(P>0.05)。结论:血清Cys C和24 h U-mAlb在慢性肾小球肾炎早期肾功能损害时升高均较为灵敏,二者可作为慢性肾小球肾炎早期肾功能损害评估的敏感指标。Objective： To study the clinical significance of the serum Cystatin C （Cys C） and uric microalbumin within 24 hours （24 h U-mAlb） in the early renal impairment of the patients with chronic glomerulonephritis. Methods： The serum Cys C and 24 h U-mAlb of 43 patients with chronic glomerulonephritis （observation group） were detected and compared with those of 43 healthy subjects （control group）. Results： The serum Cys C and 24 h U-mAlb in the observation group were higher remarkably than those in the control group （P〈0.05）. There was no significant difference in detecting rate of the serum Cys C and 24 h U-mAlb in patients with chronic glomerulonephritis （P〉0.05）. Conclusion： The serum Cys C and 24 h U-mAlb are all sensitive in evaluating the renal impairment of the patients with chronic glomerulonephritis, and can become two sensitive indicators for evaluating the early renal impairment of the patients with chronic glomerulonephritis.

关 键 词：慢性肾小球肾炎 血清胱抑素C 尿微量白蛋白 

分 类 号：R692.3[医药卫生—泌尿科学]