伴雷诺现象的结缔组织病25例临床分析  

Clinical analysis of Raynaud’s phenomenon in patients with connective tissue disease

作　　者：赵顺芳[1] 何敏华[2] 杜茜茹[3] 

机构地区：[1]大理学院附属医院心内科,云南大理671000 [2]大理学院附属医院风湿免疫肾脏科,云南大理671000 [3]大理学院附属医院呼吸内科,云南大理671000

出　　处：《海南医学》2011年第23期112-113,共2页Hainan Medical Journal

摘　　要：目的探讨伴雷诺现象(RP)的结缔组织(CTD)患者临床特征、治疗及预后转归。方法对2005-2010年在我院住院的伴RP的25例CTD患者的临床表现、治疗方法、结果及其预后进行回顾性分析与总结。结果伴RP的CTD患者经一般治疗、治疗原发疾病和扩血管、活血化瘀等,其总有效率为92%,但1例因反复发作心衰死亡,1例伴RP的类风湿性关节炎(RA)患者猝死。结论 CTD患者出现RP提示较易发生肺动脉高压,心脏受累和免疫学异常,预后较差。对伴RP的CTD患者应注意其心肺状态,早期诊断和治疗,以防不良后果发生。Objective To explore the clinical manifestations, treatment of patients with connective tissue disease （CTD） presenting with Raynaud＇ s phenomenon （RP）. Methods We retrospectively analyzed the clinical manifestations, treatment and prognosis of 25 CTD patients with RP admitted consecutively in the Affiliated Hospital of Dali University from 2004 to 2009. Results Through general treatment, vasodilatation and promoting circulation treatment, the total effective rate was 92% for CTD patients with PP. However, one patient died of repeated heart failure, and another patient with rheumatoid arthritis （RA） died of sudden death. Conclusion Patients with CTD presenting with RP were susceptible to pulmonary hypertension, cardiac involvement and immunologic abnormalities, and the prognosis is poor. We should pay special attention to the pulmonary and heart function in CTD patients with R.P, in order to avoid unfavorable consequences.

关 键 词：雷诺现象 结缔组织病 自身免疫疾病 

分 类 号：R593.2[医药卫生—内科学]