正交试验法优选痛经颗粒水提工艺  

Study on Optimizing Technological Condition of Water Extraction for Tongjing keli by Orthogonal Design

作　　者：卜绥云 王静[2] 胡锦鹏[3] 陈萍[3] 柴焱[2] 

机构地区：[1]榆林市食品药品稽查大队,陕西榆林719000 [2]陕西中医学院,陕西咸阳712046 [3]陕西省中医药研究院,陕西西安710003

出　　处：《中医药导报》2011年第11期72-73,共2页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:优化痛经颗粒中芍药苷的最佳提取工艺。方法:以白芍中芍药苷的提取率和浸膏得率为指标,采用L9(34)正交试验法优选痛经颗粒中芍药苷的最佳提取工艺。结果:优选的最佳提取工艺为:第1次加10倍量的水,煎煮1.5 h,第2次加8倍量的水,煎煮1.5 h,第3次加6倍量的水,煎煮0.5 h。结论:该水提工艺设计合理,芍药苷提取率高,稳定可行,方法可重复操作,可为痛经颗粒的研制提供理论和试验基础。Object： To optimize the water extraction process of Tongjing keil.Method： Orthogonal design was used to select the water extraction process of Tongjing keli with the content of the content of paeoniflorin and mellow dry extracting rates.Resule： The best water extraction process of Tongjing keil was： the frist time adding 10 folds water,decocting 1.5 h,adding 8 folds water for second,decocting 1.5 h,and adding 6 folds water for second,decocting 0.5 h.Conclusion：The established technology was reasonable,fesible and reproducible.It can be used for the development Tongjing keil to provide theoretical and experimental basis.

关 键 词：痛经颗粒 水提工艺 芍药苷 干膏得率 正交试验 

分 类 号：R284.2[医药卫生—中药学]