单微粒三维纳米级实时定位算法的研究  

Research on 3D Localization of Single Particle in Real-time with Nano-precision

作　　者：曲峰[1] 瞿安连[1] 

机构地区：[1]华中科技大学生物物理与生物化学研究所,武汉430074

出　　处：《计算机与数字工程》2011年第11期130-133,共4页Computer & Digital Engineering

摘　　要：单微粒定位技术为研究纳米微粒的动力学特性提供了重要手段。文章通过研究纳米微粒的离焦图像,分析计算出离焦图像与离焦距离的关系。由此开发出单微粒三维纳米级实时定位算法,为研究复杂环境中纳米微粒的动力学特性提供了有效地研究手段。Single particle localization is very important for studying dynamics of nanoparticles.In this paper,off-focus images of nanoparticles were analyzed and the relationship between off-focus images and defocus distance was calculated.Thus we developed an algorithm for 3D localization of single particle in real-time with nano-precision.This provide effective method for study dynamics of nanoparticles in complex environments.

关 键 词：单微粒定位 离焦图像 离焦距离 

分 类 号：TP301.6[自动化与计算机技术—计算机系统结构]