血脂检测在细菌性肺炎与支原体肺炎鉴别诊断中的作用  

The effect of blood lipid test in the diagnosis of bacterial pneumonia and mycoplasma pneumonia

作　　者：黎运西[1] 林超群[1] 谢健敏[1] 张成禄[1] 秋辉[1] 罗秀玲[1] 黎文生 

机构地区：[1]广东省佛山市顺德区第一人民医院检验科,528300 [2]广东省佛山市顺德区第一人民医院心血管内科,528300

出　　处：《检验医学与临床》2011年第22期2697-2698,2700,共3页Laboratory Medicine and Clinic

基　　金：佛山市科技局医学类科技攻关项目(201008201)

摘　　要：目的分析细菌性肺炎和支原体肺炎患者血脂水平的差异,探讨血脂检测在细菌性肺炎与支原体肺炎辅助鉴别诊断中的价值。方法采用酶耦联比色法、免疫比浊法、终点比色法对77例细菌性肺炎、72例支原体肺炎患者和78例健康体检人群的中性粒细胞、胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(ApoA1)、ApoB、清蛋白(ALB)和C反应蛋白(CRP)浓度进行检测。结果与健康体检人群比较,细菌性肺炎患者TC、HDL-C、LDL-C、ApoA1、ApoB显著降低,差异有统计学意义(P<0.01);与支原体肺炎患者比较,细菌性肺炎患者TC、HDL-C、LDL-C、ApoA1、ApoB显著降低,差异有统计学意义(P<0.01);支原体肺炎患者TC、HDL-C和ApoA1浓度较健康人显著降低,差异有统计学意义(P<0.01)。结论血脂水平在细菌性肺炎和支原体肺炎中有显著性差异;血脂水平的检测对细菌性肺炎和支原体肺炎的辅助诊断及鉴别诊断有重要意义。Objective To observe the difference of blood lipid level between bacterial pneumonia and mycoplasma pneumonia（MP）,and to investigate the value of blood lipid test in the diagnosis of bacterial pneumonia and MP.Methods The neutrophils,TC,TG,HDL-C,LDL-C,ApoA1,ApoB,ALB and CRP of 77 patients with bacterial pneumonia,72 patients with MP and 78 healthy people were tested by enzyme-colorimetric method,immunoturbidimetry assay,and end point assay respectively.Results Concentrations of TC,HDL-C,LDL-C,ApoA1 and ApoB in plasma of patients with bacterial pneumonia were significantly lower than those in MP and healthy people.The concentrations of TC,HDL-C and ApoA1 in plasma of patients with MP were significantly lower than those in healthy people.Conclusion Blood lipid and neutrophils level in bacterial pneumonia and MP are significantly different and blood lipid detection might be used to differentiate bacterial pneumonia from MP.

关 键 词：血脂 细菌性肺炎 支原体肺炎 

分 类 号：R725.631[医药卫生—儿科]