分离胶促凝管对10项生化检测项目影响的比对研究  

The comparative analysis of the results on 10 biochemical terms by the separating gel coagulation-promoting vacuum tube

作　　者：潘永康[1] 降海涛 

机构地区：[1]广东省开平市中心医院,529300 [2]广东省广州市阳普医疗科技股份有限公司,510530

出　　处：《检验医学与临床》2011年第22期2757-2758,共2页Laboratory Medicine and Clinic

摘　　要：目的通过与无抗凝管做比对,观察分离胶促凝管对丙氨酸氨基转移酶(ALT)、总蛋白(TP)等10项生化检测项目的影响,判断两种管在10项生化检测项目上是否实质等同。方法按照美国临床和实验室标准协会的EP9-A2文件要求,以无抗凝管为参比方法(X),以分离胶促凝管为待比方法(Y),用随机抽取的血清样本对上述10项生化项目分别进行检测,计算相关系数及直线回归方程,以CLIA′88规定的室间质量评价允许误差范围的1/2为标准,判断不同检测系统的偏差临床是否可以接受性。结果在所检测的项目中,两种管子检测结果的偏差均在临床可接受范围内。结论在ALT等10项生化检测项目上,分离胶促凝管和无抗凝管可以实质等同。Objective To observe the influence on 10 biochemical terms（including ALT,TP,etc.） by comparing to the no additional tube,and to estimate if two tube can be considered as the same on 10 biochemical terms.Methods Following CLSI document EP9-A2,10 terms were detected using the serum drawed in random.No additional tube was used as the comparative method（X）,with gel coagulation-promoting vacuum tube（Y） separated.the correlation coefficient and the linear equation was obtained.Then the coefficient and the equation were used to evaluate the system bias between laboratory method and comparison method.we judged the comparability of different investigating systems according to half of the CLIA′88 standard.Results The 10 biochemical terms and the SE of the two tubes were in the clinical acceptable range.Conclusion In 10 biochemical terms,the separating gel coagulating-promoting tube and no additional tube can be considered as the same virtually.

关 键 词：无抗凝管 分离胶促凝管 血清 

分 类 号：R446.1[医药卫生—诊断学]