吸毒与丙型肝炎病毒、人类免疫缺陷病毒及梅毒螺旋体感染的相关性研究  

Relative study of hepatitis C virus,human immunodeficiency virus and treponema pallidum infection in drug addicts

作　　者：梁纲[1] 黄绍标[2] 李飞 李荣建[4] 吴锋耀[2] 凌敏[1] 陈万[2] 尤宗省[1] 

机构地区：[1]广西医科大学,南宁530021 [2]南宁市第四人民医院 [3]南宁市公安局戒毒所 [4]广西疾病预防控制中心

出　　处：《山东医药》2011年第44期20-21,共2页Shandong Medical Journal

基　　金：广西科技厅资助课题(9811004);南宁市科技局资助课题(20091014C)

摘　　要：目的调查吸毒人群中丙型肝炎病毒(HCV)、人类免疫缺陷病毒(HIV)和梅毒螺旋体(TP)感染的情况,以便采取有效防治措施。方法对强制戒毒的313例吸毒者进行集群抽样调查,受检者除进行一般临床分析和有关功能检查外,重点检测其HCV、HIV及TP的感染强度。HCV及HIV检测采用ELISA法,TP检测采用TP颗粒凝胶(TPPA)法。结果 313例吸毒者中HCV、HIV及TP阳性者分别为267、19、18例,感染率分别为85.3%、6.1%、5.8%。其中HCV+TP、HCV+HIV两种阳性并存者感染率为4.2%、5.8%,未发现HIV+TP感染同时存在。但在本组中可见TP阳性率在青少年组不论男女明显高于其他年龄组,其男、女组阳性率分别为17.9%、11.9%。结论吸毒者是HCV、HIV、TP感染的高危人群,青少年中的TP感染者也可能成为HIV/艾滋病(AIDS)的高危人群。Objective To investigate the prevalence of hepatitis C virus （ HCV）, human immunodeficiency virus （HIV） and treponema pallidum （TP） infection in drug addicts of Guangxi province. Methods The total of 313 drug ad- dicts forced to stop drug received sampling survey. All subjects were tested the infection of HCV, HIV and TP aside from the examination of ordinary clinical and relative functions. HCV and HIV were measured by ELISA technique, TP was measured by TPPA method. Results The positive rate of HCV, HIV, TP was 85.3% （267/313）, 6.1% （19/313） and 5.8% （18/313） respectively. The positive rate of both HCV and TP, both HCV and HIV was 4.2% and 5.8% respectively, but simultaneous infection of HIV and TP wasn＇ t found. TP infection in teen-agers group showed higher positive rate than that in the other age groups, the positive rate in boys and girls was 17.9% and 11.9% respectively. Conclusions Drug addicts are high-risk crowd of HC~, HIV and TP infection. Teen-agers of TP infection may be the high-risk crowd of HIV/AIDS.

关 键 词：吸毒 肝炎病毒 丙型 人类免疫缺陷病毒 梅毒 

分 类 号：R51[医药卫生—内科学]