北京地区儿童末梢血5种微量元素检测结果分析  

Analysis on the results of five trace elements in peripheral blood of children in Beijing

作　　者：吕葛[1] 宋文琪[1] 徐樨巍[1] 

机构地区：[1]首都医科大学附属北京儿童医院检验中心,100045

出　　处：《中华检验医学杂志》2011年第11期975-978,共4页Chinese Journal of Laboratory Medicine

摘　　要：目的了解北京地区儿童钙、铜、锌、铁、镁5种微量元素含量的分布和变化规律，为防治儿童缺乏微量元素提供参考依据。方法采用原子吸收光谱仪对2010—2011年在北京儿童医院体检的7972名儿童末梢血的钙、铜、锌、铁、镁5种微量元素进行检测。受检儿童均为北京城区常住人口，将其分为5个年龄组：婴儿组（1～12个月，1506名），幼儿组（1～2岁，2766名），学龄前组（3～6岁，1918名），学龄期组（7～11岁，1576名），青春发育期组（12～18岁，206例），每组按性别又分成男、女2组。对不同年龄段和不同性别间儿童5种微量元素分布情况进行分析。结果末梢血微量元素钙和铜的含量随年龄增长呈下降趋势，而锌和铁的含量呈上升趋势，血镁的含量较稳定。婴儿期男性和女性组铜的含量分别为（21．90±2．89）和（21．25±2．80）μmol／L，幼儿期分别为（21．76±2．78）和（21．29±2．69）μmol／L，学龄前期分别为（21．32±2．83）和（20．88±2．84）μmol／L，学龄期分别为（20．81±3．02）和（20．36±3．37）μmol／L，不同性别儿童间的差异均有统计学意义（t值分别为4．640、4．475、3．290、2．894，P均〈0．01），而青春发育期分别为（19．53±2．91）和（20．30±2．90）μmol／L，差异无统计学意义（t=-1．796，P〉0．05）；钙、锌、铁、镁含量在相同年龄段不同性别间差异均无统计学意义。5种微量元素中锌、铁的缺乏在不同年龄段都较为常见，总的缺乏率分别为58．9％和19．2％，婴儿期锌和铁的缺乏率分别达67．7％和42．3％。结论北京地区儿童末梢血钙、铜、镁分布水平趋于合理，铁和锌存在不同情况的缺乏，应加强对铁和锌缺乏的保健指导。Objective To provide a reference for prevention of trace elements deficiency in children by investigating the distribution and variation law of Ca, Cu, Zn, Fe, Mg of children in Beijing area. Methods Five kinds of trace elements （ Ca, Cu, Zn, Fe, Mg） in peripheral blood of 7 972 children of Beijing Children＇s Hospital for health examination from 2010 to 2011 were detected by atomic absorption spectrometer. The children were Beijing urban residents. They were divided into five age groups： infancy group （ 1 - 12 months, 1 506 cases） , toddler age group （ 1 - 2 years, 2 766 cases） , preschool age group （3 - 6 years, 1 918 cases） , school age group （7 -11 years, 1 576 cases） and adolescence group （12 -18 years, 206 cases）. According to gender, each group was sub-divided into male and female group. The distributions of the 5 kinds of trace elements were analyzed among different age and gender groups. Results With the age increasing, the trend of the levels of Ca and Cu were downward , but the levels of Zn and Fe were upward, and the level of Mg was stable. For boys and girls, the levels of Cu in infancy group were （21.90 ±2. 89） and（21.25 ± 2. 80） μmol/L; in toddler age group, they were （21.76 ±2. 78） and （21.29 ±2. 69） μmol/L; in preschool age group, they were （21.32± 2. 83 ） and （ 20. 88± 2.84 ） μmol/L; and in school age group, they were （20. 81 ± 3.02 ） and （ 20. 36± 3.37 ） μmol/L, respectively. The distribution of Cu showed significantly different among different gender groups （ t = 4. 640, 4. 475, 3. 290, 2. 894 ; P 〈 0. 01 ）. In adolescence group, the levels of Cu were （ 19.53 ± 2. 91 ） and（ 20. 30± 2. 90） μmol/L for boys and girls respectively and there was no significant difference （t = - 1. 796,P 〉 0. 05）. In each gender group, the content of Ca, Zn, Fe, and Mg was not significantly different between boys and girls. It was common for the deficiency of Zn and Fe in all ages. Their total deficiency rates were 58.9% an

关 键 词：痕量元素 末梢血 儿童 

分 类 号：R179[医药卫生—妇幼卫生保健]