男性非淋患者CT DNA和UU DNA流行病学比较  

Epidemiological comparison of UU DNA and CT DNA in male patients with non-gonococcal urethritis

作　　者：欧阳耀灵[1] 杨光华[1] 彭长华[1] 

机构地区：[1]湖北省荆州市中心医院,湖北荆州434020

出　　处：《中国卫生检验杂志》2011年第11期2701-2702,2776,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:为了研究男性非淋患者CT DNA和UU DNA流行病学特征。方法:FQ-PCR用于定量检测男性生殖道样本中的UU DNA和CT DNA。结果:非淋病原体感染率UU DNA(26.64%,517/1941)显著高于CT DNA(9.26%,177/1911)(χ2=196.78,P=1.05E-44),而载量比较显示UU DNA(4.47±1.36)显著低于CT DNA(4.72±1.85)(t=4.913,P=9.47E-7);UU DNA阳性率逐年上升(r=+0.87,p=0.028),载量逐年下降(r=-0.75,P=0.020);CT DNA阳性率无统计学变化(r=+0.48,P=0.19),载量逐年下降(r=-0.88,P=0.0016)。结论:UU是男性非淋菌性尿道炎的主要病原体,CT急性感染的比例高于UU,UU感染流行有增加的趋势,CT感染趋势较为稳定。Objective：To study the epidemiological characteristics of UU DNA and CT DNA in male patients with non-gonococcal urethritis.Methods： FQ-PCR was used for the quantitative detection of UU DNA and CT DNA in the sample of the male patients with non-gonococcal urethritis.Results： The positive rates of UU DNA（26.64%,517/1941） was higher than CT DNA（9.26%,177/1911）（χ2=196.78,P=1.05E-44）,the load of UU DNA（4.47±1.36）was lower than the CT DNA（4.72±1.85）（t=4.913,P=9.47E-7）;The positive rates of UU DNA increased（r=＋0.87,P=0.028）while the load went down（r=-0.75,P=0.020） year by year;The positive rates of CT DNA has no difference in statistics（r=＋0.48,P=0.19） while the load went down year by year（r=-0.88,P=0.0016）.Conclusion： UU was the main pathogen of non-gonococcal urethritis for man.The proportion of acute infection by the CT were higher than that by the UU,the infection rate of the UU increased while that of CT was stable.

关 键 词：解脲支原体DNA 沙眼衣原体DNA 男性非淋菌性尿道炎 FQ-PCR 

分 类 号：R695[医药卫生—泌尿科学]