肌红蛋白测定对早期心肌损伤的诊断价值  

Determination of Myoglobin in the Early Diagnosis of Myocardial Injury

作　　者：王志峰 梁勇 

机构地区：[1]江苏省南通市通州中医院检验科,江苏南通226300

出　　处：《黑龙江医学》2011年第11期861-863,共3页Heilongjiang Medical Journal

摘　　要：目的观察急性心肌梗死(AMI)患者血清中肌红蛋白(Mb)及心肌酶谱浓度、异常阳性检出率,探讨Mb在AMI早期诊断中的价值。方法动态检测45例AMI患者血清中Mb和及心肌酶谱浓度,并与23例非AMI胸痛患者比较。结果 45例AMI患者血中Mb峰值在4～8 h出现,浓度达(796±364)μg/L,且发病12 h内异常阳性检出率达90%以上。CK和CK-MB峰值约在24 h,持续2～3 d。23例对照组患者Mb水平无明显变化。结论 Mb在AMI中出现时间早,浓度可达正常值的几十倍,可做为AMI早期诊断的重要指标,其动态监测更可做为AMI病情和疗效观察的重要依据。Objective To observe the acute myocardial infarction（AMI） patients with serum myoglobin（Mb） and myocardial enzyme levels,abnormal positive detection rate of Mb in the value of early diagnosis of AMI.Methods Dynamic detection of 45 cases of AMI patients and myocardial enzymes in serum Mb and concentration,and with 23 more cases of non-AMI chest pain patients.Results 45 patients with AMI were peak serum Mb appeared in 4~8 h,the concentration of（796±364）μg/L,and within 12 h of onset of abnormal positive detection rate of 90%.CK and CK-MB peak at about 24 h,last 2~3 d.23 cases of control group patients Mb did not change significantly.Conclusion Mb in AMI appeared early,the concentration of up to several times the normal value not only be used as an important indicator of early diagnosis of AMI,but also its dynamic monitoring of the disease and efficacy of AMI as an important basis.

关 键 词：急性心肌梗死 肌红蛋白 心肌损伤标志物 

分 类 号：R446.1[医药卫生—诊断学]