颈动脉粥样硬化斑块超声造影特征分析  

Contrast Enhanced Ultrasound Imaging of Carotid Atherosclerotic Plaques

作　　者：白志勇[1] 李敬府[1] 杨玉杰[1] 张华斌[1] 刘蕾[2] 李小刚[2] 贾建文[1] 

机构地区：[1]北京大学第三医院超声科,北京市100191 [2]北京大学第三医院神经内科,北京市100191

出　　处：《中国超声医学杂志》2011年第11期994-996,1044,共4页Chinese Journal of Ultrasound in Medicine

基　　金：教育部留学回国人员科研启动基金(No.19-850-600)

摘　　要：目的探讨颈动脉斑块超声造影增强特征。方法对136例患者颈动脉斑块进行超声造影,分析增强特征与斑块回声、厚度及狭窄的关系。结果 (1)低、混合、中等和强回声斑块出现增强的比例分别为59.6%、57.6%,36%和13.5%,组间P<0.01。(2)厚度≤2 mm、2.1～3.0 mm、3.1～4.0 mm和>4.0 mm组斑块增强比例分别为15.9%、45.3%、63.0%和65.9%,后两组高于前两组P<0.01。(3)颈内动脉轻、中、重度狭窄组,斑块增强比例分别为35.0%、56.0%和60.7%,中、重度狭窄组高于轻度狭窄组,P<0.01。结论超声造影可以显示斑块内新生血管,其增强程度与斑块回声、厚度和颈动脉狭窄有相关性。Objective To study the enhancement characteristics of carotid plaques by contrast enhanced ultra- sound （CEUS）. Methods Carotid atherosclerosis plaques of 136 persons were imagined with CEUS. The correlation of plaques echogenicity, thickness and stenosis with enhancement were analyzed. Results （1） The enhancement per- centage of hypo-, hetero-, iso- and hyper-echogenicity plaques were 59.6% ,57.6%,36%, and 13.5% respectively, P〈0.01. （2） The enhancement percentage of plaques with thickness 42 ram,2.1-3.0 ram,3.1-4.0 mm,〉4.0 mm were 15.9 %, 45.3 %, 63.0 %, 65.9% respectively, enhancement percentage of the last two groups were higher than that of the other two groups, P〈0. 01. （3） Enhancement percentage of plaque with mild, moderate, serious stenosis were 35.0%, 56.0%, 60.7% respectively,plaque Enhancement percentage of mild stenosis were less than that of another two group, P〈0.01. Conclusions Carotid intraplaque neovascularization could be detected by CEUS, the enhancement had correlation with echogenicity, thickness and stenosis.

关 键 词：超声造影 颈动脉 粥样硬化 

分 类 号：R445.1[医药卫生—影像医学与核医学]