血管回声跟踪技术检测慢性肾脏病患者颈总动脉及桡动脉弹性变化  

Detecting Carotid Artery and Radial Artery of Chronic Kidney Disease Patients by Echo-tracking Technique

作　　者：郭卫东[1] 白亚玲[2] 张晓玲[3] 赵刚[1] 徐金生[2] 杨漪[4] 

机构地区：[1]河北医科大学附属石家庄市第三医院功能科,石家庄市050011 [2]河北医科大学第四医院肾内科 [3]沧州医学高等专科学校 [4]河北医科大学第四医院超声科

出　　处：《中国超声医学杂志》2011年第11期1005-1008,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨血管回声跟踪技术检测慢性肾脏病(chronic kidney disease,CKD)患者颈总动脉(common carotid artery,CCA)和桡动脉(radial artery,RA)弹性的意义。方法应用超声血管回声跟踪(echo-tracking,ET)技术检测100例各期CKD患者CCA及RA弹性的变化,并与正常对照组比较,分析不同部位动脉间弹性变化的差异,以及评价CKD患者的变化规律。结果 (1)随患者病程发展,参数僵硬度指数(stiffness parameter,β),血管压力-应变弹性系数(pressure-strain elastictymodulus,Ep),点脉搏波传导速度(one-point pulse wave velocity,PWVβ)呈逐渐增大变化,顺应性(arterial compliance,AC)呈逐渐减小趋势。(2)按照肾损伤的程度分组后发现,桡动脉的β、Ep、PWVβ、AC的变化,在中度组即与轻度组有统计学意义(P<0.05)。颈总动脉在中度组与轻度组比较只有PWVβ有统计学意义(P<0.05),而β、Ep和AC的变化无统计学意义(P<0.05),在重度组才与轻度组有统计学意义(P<0.05)。结论 ET技术能够准确检测CKD患者早期动脉弹性的改变,较准确反映CKD的病情,是评价早期动脉硬化简便实用的方法。RA弹性参数变化早于CCA参数变化,说明肌性外周动脉可能是反映早期动脉弹性改变的更为敏感指标。Objective To investigate the value of echo-tracking technique detecting carotid artery and radial artery elasticity of CKD patients. Methods Carotid artery and radial artery elasticity changes of 100 chronic kidney disease patients and normal control group were detected by ultrasound echo-tracking（ET） technique. The elasticity of different arteries and changing laws of chronic kidney patients were analyzed. Results （1）With the progression of dis- ease course, Stiffness parameter （β） of ET technique, vascular pressure strain elasticty modulus （Ep）, one-point pulse wave velocity （PWVβ） gradually increased. Arterial compliance（AC） showed a decreasing tendency. （2）There were statistical differences （P〈0.05） in β. Ep. PWVβ. AC changes of RA in the mild group and moderate group. Only PWVβ of CCA in the moderate group and the mild group had statistical difference （P〈0.05）. β. Ep. AC had, statistical differences （P〈0.05） only in the severe group. Conclusions ET technique can accurately detect early chan ges in arterial elasticity of CKD patients. RA have significant changes in the moderate group （CKD3）, which occurs earlier than CCA parameters. It is indicated that muscular peripheral artery may be the sensitivc indicators in reflecting the early changes of arterial elasticity.

关 键 词：慢性肾脏病 血管回声跟踪技术 颈总动脉 桡动脉 动脉弹性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R692[医药卫生—诊断学]