子宫内膜异位症生育指数与相关不孕患者腹腔镜术后妊娠的相关性  

Relationship between endometriosis fertility index and pregnancies after laparoscopic surgery inendometriosis-associated infertility

作　　者：魏代敏[1] 郁琦[1] 孙爱军[1] 田秦杰[1] 陈蓉[1] 邓成艳[1] 孙正怡[1] 甄璟然[1] 何方方[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院妇产科,北京100730

出　　处：《中华妇产科杂志》2011年第11期806-808,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的评价子宫内膜异位症（内异症）生育指数与内异症不孕患者腹腔镜术后妊娠的相关性。方法回顾性分析2005年1月至2010年1月350例行腹腔镜手术治疗的内异症相关不孕患者的病史及手术资料，电话随访其术后的妊娠情况。按照内异症生育指数的评分标准计算生育指数，利用Kaplan—Meier生存分析法计算不同分值患者的累积妊娠率，并进行比较。结果内异症生育指数8、9、10分患者术后36个月的累积妊娠率分别为62．5％、69．8％、81．1％，3者间比较，差异无统计学意义（P=0．24）；5、6、7分患者术后36个月累积妊娠率分别为49．8％、43．9％、41．6％，3者间比较，差异也无统计学意义（P=0．83）。但8—10分患者术后36个月的总累积妊娠率为71．8％，5—7分患者为44．4％，两者比较，差异具有统计学意义（P：0．ooo）。0—4分患者例数较少（共33例），其中15例妊娠。结论内异症生育指数与内异症相关不孕患者腹腔镜术后的妊娠率相关。内异症生育指数对指导术后处理的选择具有重要的临床意义。Objective To evaluate the relationship between endometriosis fertility index （EFI） and pregnancies after laparoscopic surgery in endometriosis-assoeiated infertility. Methods From Jan. 2005 to Jan. 2010, medical documents of 350 infertile patients due to endometriosis undergoing laparoscopie surgery were studied retrospectively. Pregnancy outcomes were followed up by telephone. EFI was calculated by history factors, least function score and some aspects of the revised American Fertility Society （ r-AFS ） endometriosis stage. The cumulative pregnancy rate was calculated and compared by Kaplan-Meier survival analysis. Results Within 3 years after surgery, the cumulative pregnancy rates among patients with EFI score 8,9, 10 were 62. 5%, 69. 8% and 81. ]%, respectively. There was no significant difference in pregnancy rates among those three groups of patients （ P = 0. 24 ）. The cumulative pregnancy rates among patients with EFI score 5,6,7 were 49. 8%, 43.9% and dl. 6%, respectively, which did not reach statistical difference （ P = O. 83 ）. The cumulative pregnancy rates of EFI score 8 - 10 was significantly higher than that of EFI score 5 -7 （71.8% vs. 44. 4% , P=O. 1300）. The patients with EFI score 0 -4 was quite small with only 33 cases, among which 15 cases were pregnant. Conclusions There is relationship between EFI and pregnancy in patients with endometriosis-associated infertility. EFI is meaningful to guide post- surgical treatment.

关 键 词：子宫内膜异位症 不育 女(雌)性 生育力 腹腔镜检查 妊娠结局 

分 类 号：R711.71[医药卫生—妇产科学]