320排CT曲面重组肝脏灌注成像的可行性研究  

320 multidetector CT curved planar reformation technique in hepatic perfusion imaging

作　　者：刘家祎[1] 温兆赢[1] 张兆琪[1] 晏子旭[1] 

机构地区：[1]首都医科大学附属安贞医院放射科,北京100029

出　　处：《放射学实践》2011年第11期1189-1192,共4页Radiologic Practice

摘　　要：目的:探讨320排CT全肝灌注成像结合肝脏曲面重组(CPR)技术临床应用的可行性和价值。方法:36例患者(正常肝脏20例,肝细胞癌16例)行CT动态容积扫描,经图像后处理分别获得横轴面和曲面重组肝脏灌注图像。结果:正常肝脏在CPR和横轴面图像上测得的肝动脉灌注(HAP)值分别为(29.3±6.3)和(31.1±5.0)ml/(min.100ml),门静脉灌注量(PVP)分别为(96.1±15.2)和(94.3±12.7)ml/(min.100ml),肝灌注指数(HPI)为(23.4±5.8)%和(24.8±6.2)%,BF分别为(125.4±15.2)和(124.5±15.6)ml/(min.100ml),TTP分别为(19.2±3.2)s和(20.8±2.8)s;肝细胞癌在CPR和横轴面图像上测得的HAP分别为(61.8±5.7)和(62.3±5.3)ml/(min.100ml),PVP分别为(32.8±4.5)和(33.4±5.3)ml/(min.100ml),HPI分别为(65.3±6.1)%和(66.1±6.7)%,BF分别为(254.8±20.5)和(257.4±21.8)ml/(min.100ml),TTP分别为(11.2±3.2)s和(11.9±3.8)s,在CPR和横轴面图像上测量的各项灌注参数差异均无显著性意义(P>0.05)。结论:肝脏CPR和常规横轴面灌注图像的诊断能力相同,但CPR灌注图像可以保证在同一图像上同时显示主动脉、门静脉、脾脏及肝内任意部位的病变,尤其对远离肝门的病变具有明显优势。Objective：To investigate the clinical application and the value of 320 multidetector CT（MDCT） curved planar reformations（CPR） in hepatic perfusion.Methods：Thirty-six patients were analyzed.There were 20 patients in normal group,16 patients in hepatic cancer group.All patients underwent dynamic volume CT scan,then axial and CPR images were reconstructed separately to perfusion data at same location.Results：The HAP,PVP,BF,HPI and TTP measured from normal group were：（29.3±6.3）,（96.1±15.2） and（125.4±15.2）ml/（min·100ml）,（23.4±5.8）% and（19.2±3.2）s on CPR images.The corresponding perfusion data measured from normal group were：（31.1±5.0）,（94.3±12.7） and（124.5±15.6）ml/（min·100ml）,（24.8±6.2）% and（20.8±2.8）s,respectively,on axial images.The perfusion data measured from hepatic cancer group were：（61.8±5.7）,（32.8±4.5） and（254.8±20.5）ml/（min·100ml）,（65.3±6.1）% and（11.2±3.2）s on CPR images.The corresponding perfusion data measured from hepatic cancer group were：（62.3±5.3）,（33.4±5.3） and（257.4±21.8）ml/（min·100ml）,（66.1±6.7）% and（11.9±3.8）s,respectively,on axial images.There were no significant difference（P0.05） between the CPR and axial perfusion data.The TDC was similar between the axial and CPR perfusion of the same patients.Conclusion：There was no significant difference between the axial and CPR perfusion in diagnosing liver diseases.But aorta,portal vein,spleen and lesion in any position of the liver can be shown on one CPR perfusion image,especially lesions far from hepatic portal of liver.

关 键 词：肝脏 体层摄影术 X线计算机 图像处理 计算机辅助 灌注成像 

分 类 号：R816.5[医药卫生—放射医学]