曲美他嗪对冠心病合并糖尿病PCI术后患者再发心绞痛的作用  被引量:5

Effect of trimetazidine on recurrence angina pectoris in coronary heart disease patients with diabetes after percutaneous coronary intervention

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作  者:赵立[1] 张怀金[1] 吕留强[1] 王广川[1] 唐杨章[1] 

机构地区:[1]安徽省淮北市人民医院心内科,淮北235000

出  处:《临床医学》2011年第9期15-16,共2页Clinical Medicine

摘  要:目的评价曲美他嗪对冠心病合并糖尿病经皮冠状动脉介入治疗(PCI)术后患者再发心绞痛的干预作用。方法将60例冠心病合并糖尿病PCI术后再发心绞痛患者随机分为常规治疗组和曲美他嗪组,进行相关对比研究。结果两组治疗4周后,心绞痛发作频率、持续时间较治疗前均明显减少(P<0.05),曲美他嗪组更明显,而且无明显不良反应,血糖稳定,两组间的心率、血压比较差异无统计学意义(P>0.05)。结论曲美他嗪可明显减少冠心病合并糖尿病PCI术后患者心绞痛发作次数及持续时间,改善心功能,且血糖稳定,对心率、血压无影响,安全有效。Objective To evaluate the effect of trimetazidine on recurrence angina pectoris in coronary heart disease(CHD) patients with diabetes mellitus after percutaneous coronary intervention(PCI). Methods Sixty recurrence angina pectoris patients with coronary heart disease and diabetes after percutaneous coronary intervention were randomly divided into the routine treatment group and trimetazidine group,then relative comparative study was made. Results After anginal attack frequency,duration were significantly reduced 4 weeks after treatment than before treatment of the two groups(P0.05),however trimetazidine group was more obvious,and hade no obvious adverse reactions,blood glucose was stable.There was no significant differences in heart rate blood pressure between the two groups(P0.05). Conclusion Trimetazidine can obviously reduce anginal attacks and duration,improve heart function of post-PCI patients with diabetes mellitus and CHD,and blood glucose was stable.It had no effect on heart rate,blood pressure,and it was safe and effective.

关 键 词:曲美他嗪 冠心病 糖尿病 经皮冠状动脉 血管成形术 

分 类 号:R541.4[医药卫生—心血管疾病] R587.1[医药卫生—内科学]

 

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