Sulfamic acid as a reusable and green catalyst for efficient and simple synthesis of 2-substituted-2,3-dihydroquinazolin-4(1H)-ones in water or methanol  

作　　者：Amin Rostami Ashkan Tavakoli 

机构地区：[1]Department of Chemistry Faculty of Science,University of Kurdistan,Sanandaj 6617715143,Iran

出　　处：《Chinese Chemical Letters》2011年第11期1317-1320,共4页中国化学快报（英文版）

摘　　要：A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild conditions.The reaction was efficiently promoted by 10 mol%sulfamic acid（SA,H_2NSO_3H） and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild conditions.The reaction was efficiently promoted by 10 mol%sulfamic acid（SA,H_2NSO_3H） and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.

关 键 词：Sulfamic acid Catalyst ANTHRANILAMIDE Aldehyde Ketone 2 3-Dihydroquinazolin-4（1H）-ones 

分 类 号：O621.3[理学—有机化学]