137例药品不良反应报告分析  

Report of Adverse Drug Reactions:Analysis of 137 Cases

作　　者：陈小佳[1] 刘贤铭[1] 

机构地区：[1]江苏省肿瘤医院,南京210009

出　　处：《中国医院用药评价与分析》2011年第11期1043-1046,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解江苏省肿瘤医院药品不良反应(ADR)发生的特点,为临床合理用药提供参考。方法:对2008年6月—2011年6月收集的137例ADR报告分别从患者年龄、性别、给药途径、引起ADR的药品种类、涉及器官和(或)系统以及临床表现等方面进行统计分析。结果:137例ADR涉及55种药品,其中抗感染药所致ADR居首位(44例,占32.12%),其次是抗肿瘤药(33例,占24.09%);给药途径以静脉滴注为主(108例,占78.83%);ADR临床表现以皮肤及其附件损害最常见(49例,占25.65%)。结论:应加强ADR报告和监测工作,合理使用药物,避免ADR的重复发生。OBJECTIVE：To probe into the characteristics of the adverse drug reactions（ADRs） in Jiangsu Provincial Tumor Hospital so as to provide reference for clinic rational drug use.METHODS： A total of 137 ADR cases collected from June 2008 to June 2011 were statistically analyzed in respect of patients＇ age and sex,route of administration,categories of drugs that induced ADR,the organs or systems involved and the clinical manifestations etc.RESULTS： A total of 55 drugs were involved in the 137 ADR,with 44 cases（32.12%） induced by anti-infective drugs and 33（24.09%） by antineoplastic agents.108 cases（78.83%） were induced vial intravenous drip infusion.49 cases（25.65%） manifested as damage of skin and its appendants.CONCLUSION： ADR reporting and monitoring should be strengthened to achieve rational use of drugs and avoid recurrence of ADR.

关 键 词：药品不良反应 报告 分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]