抗胆碱药在慢性阻塞性肺疾病中的应用  

Anticholinergic agents in chronic obstructive pulmonary disease

作　　者：段玉香 修清玉[2] 石昭泉[2] 

机构地区：[1]上海同仁医院呼吸内科,上海200050 [2]上海长征医院呼吸内科,上海200003

出　　处：《中国新药与临床杂志》2011年第11期809-814,共6页Chinese Journal of New Drugs and Clinical Remedies

摘　　要：慢性阻塞性肺疾病(COPD)是一种以不完全可逆的气流受限为特征的慢性疾病,稳定期COPD合理应用支气管扩张药是控制该疾病症状的核心。抗胆碱药是应用于该疾病的主要支气管扩张药之一,长期而规律的抗胆碱药应用可改善患者呼吸困难,减少急性加重和恶化,降低死亡率。近年新合成的长效抗胆碱药在COPD的治疗中发挥出了更积极的作用。Chronic obstructive pulmonary disease （COPD） is a kind of chronic airway disease which is characterized by airflow limitation that is not fully reversible. Regular and right usage of bronchodilators in stable stage of COPD is the central to controlling COPD symptoms. Anticholinergic agents are one of the most effective and most important bronchodilators in COPD treatment, and long-term usage of anticholinergic agents play important roles in improving symptoms, reducing COPD acute exacerbations, and especially, lowering COPD mortality. Recently, long-acting anticholinergic agents show more active effects in COPD treatment.

关 键 词：肺疾病 慢性阻塞性 胆碱能纤维 胆碱能拮抗剂 

分 类 号：R56[医药卫生—呼吸系统]