昌吉州2005至2010年486例出生缺陷分析  

Analysis of birth defects of 486 cases in 2005-2010 in Changji

作　　者：陈筱萍[1] 李冬梅[1] 马彦华[1] 

机构地区：[1]新疆昌吉州疾病预防控制中心妇幼保健中心,新疆昌吉831100

出　　处：《中国妇幼健康研究》2011年第6期842-843,共2页Chinese Journal of Woman and Child Health Research

摘　　要：目的 了解昌吉州出生缺陷发生情况及相关因素,为制订预防出生缺陷的措施提供依据.方法 收集昌吉州辖区内各家医院2005至2010年间出生的486例缺陷儿的资料,进行回顾性分析.结果 2005至2010年出生缺陷发生率呈逐年上升趋势,2005年（5.06‰）与2010年（10.67‰）相比上升了5.61‰;年龄大于35、40岁以上妊娠者缺陷发生率分别为8.28‰、10.67‰;出生缺陷的顺位依次为神经管畸形、唇腭裂、多指趾、先天性脑积水、先心病、马蹄内翻.结论 高龄孕妇、农村地区是出生缺陷工作预防的重点,加强优生优育宣传,加强孕期系统管理,在孕前、孕早期服用小剂量叶酸片,提高产前诊断技术,是降低出生缺陷发生率的有效措施.Objective To investigate the incidence of birth defects and related factors in Changji so as to provide some basis for working out preventive measures for birth defects. Methods A retrospective study was conducted to analyze the data of 486 cases of birth defects collected from each hospital in Changji from 2005 to 2010. Results The incidence of birth defects increased year by year from 2005 to 2010, and it increased in 2010 （10.67‰） by 5.61% compared with that in 2005 （5.06 ‰）. The incidence of birth defects when pregnant women were over 35 years and over 40 years was 8.28% ‰ and 10.67%o respectively. The sequence of birth defects was neural tube defects, cleft lip and palate, polydactyly, congenital hydrocephalus, congenital heart disease and talipes equinovarus in order. Conclusion The advanced ages and rural areas are the focus of prevention work. Strengthening propaganda on prenatal and postnatal care, enhancing system management during pregnancy, taking low-dose folic acid tablets before pregnancy and at early pregnancy and improving prenatal diagnostic technique are the effective measures to reduce the incidence of birth defects.

关 键 词：出生缺陷 分析 干预措施 回顾性调查 

分 类 号：R712[医药卫生—妇产科学]