稀土联咪唑对羟基苯甲酸配合物的合成、表征及生物活性  

Synthesis,characterization and biological activity of rare earth complex with biimidazol and p-hydroxybenzoic acid

作　　者：徐莹豪[1] 陈小轲[1] 许东芳[1] 何其庄[1] 

机构地区：[1]上海师范大学生命与环境科学学院,上海200234

出　　处：《应用化工》2011年第11期1875-1877,1881,共4页Applied Chemical Industry

基　　金：国家自然科学基金资助项目(20671063);教育部资源化学重点实验室项目;稀土功能材料重点实验室项目;上海师范大学项目;上海师范大学一般科研项目(SK201048);上海市重点学科建设项目(S30406)

摘　　要：以稀土氯化镧、联咪唑和对羟基苯甲酸为原料,制备了一种新型稀土三元配合物,通过元素分析、红外光谱、紫外光谱、XRD、TEM对其进行表征,确定了该配合物的化学组成为:La(Hbiim)3N(Hbiim=2,2’-联咪唑,N=对羟基苯甲酸)。抗菌实验结果显示,三元配合物抑菌圈直径为13～17 mm,说明配合物对大肠杆菌、金黄色葡萄球菌具有一定的抑制作用,且对金黄色葡萄球菌的抑制效果较好,抗菌谱广。One ternary complex of rare earth with chloride compounds of lanthanum,biimidazol and p-hydroxybenzoic acid was synthesized in ethanol solution.The complex was characterized by elemental analysis,FTIR,UV-Vis,XRD,and TEM.The composition of the complex was confirmed to be La（Hbiim）3N.The antibacterial activities test showed that the ternary complex had antibacterial ability against Escherich coil,Staphylococcus aureus.The ternary complex exhibited antibacterial activities against Staphylococcus aureus.The antimicrobial spectrum of the complex was broad.

关 键 词：配合物 纳米 抗菌 

分 类 号：O641.4[理学—物理化学] O614.33[理学—化学]