不同碘营养水平人群甲状腺结节检测分析  

Thyroid nodule among populations with different levels of iodine nutrition

作　　者：楼晓明[1] 莫哲[1] 朱文明[1] 周金水[1] 毛光明[1] 王晓峰[1] 缪小芬[1] 丁钢强[1] 

机构地区：[1]浙江省疾病预防控制中心环境与健康监测所,杭州310051

出　　处：《中国公共卫生》2011年第12期1564-1565,共2页Chinese Journal of Public Health

基　　金：浙江省科技厅重大专项(2009C030101)

摘　　要：目的研究浙江省不同碘营养水平人群的盐碘摄入情况以及甲状腺结节的患病情况,为科学补碘提供依据。方法对纳入本次调查居民的尿碘、盐碘以及甲状腺结节患病情况进行调查,采用砷铈催化分光光度测定方法检测尿碘,硫代硫酸钠法测定盐碘,B超法检测甲状腺结节。结果共调查居民1 057人;碘适宜组、碘足量组和碘过量组盐碘摄入中位数分别为149.06、256.12、275.60μg/d,表明尿碘水平随盐碘摄入量增加而升高;甲状腺结节检出率分别为14.47%(66/456)、14.95%(48/321)、21.07%(59/280);儿童甲状腺结节检出率分别为8.89%(24/270)、9.62%(20/208)、19.80%(40/202),成人甲状腺结节检出率分别为22.58%(42/186)、24.78%(28/113)、24.36%(19/78),表明人群甲状腺结节检出率随碘摄入量增加而增加。结论人群碘营养水平处于WHO提出的适宜范围内时,甲状腺结节检出率处于较低水平。Objective To investigate the intake of salt iodine and the prevalence of thyroid nodule in the population with different levels of iodine nutrition and to provid the basis for scientific iodine supplementation.Methods The level of urinary iodine was measured with spectrophotometer method;the iodine in table salt was measured with sodium subsulfite method;the thyroid nodule was detected by Brightness mode.Results Totally 1 057 inhbitants randomly selected from 13 counties were investigated.The medians of urinary iodine for the inhabitants with adequate,above requirement,and excessive iodine nutrition were 149.06,256.12,and 275.60 μg/d,respectively.The levels of urinary iodine increased with iodine intake.The prevalence of thyroid nodule in the populations with adeguate,above requirement,and exessive iodine nutriton were 14.47%（66/456）,14.95%（48/321）,and 21.07%（59/280）,indicating that the detection rate of thyroid nodule increased with the iodine intake.Conclusion When the iodine intake is within the appropriate level proposed by WHO,the thyroid nodule detection rate is at a low level.

关 键 词：尿碘 盐碘 甲状腺结节 

分 类 号：R591.1[医药卫生—内科学]