慢性前列腺炎并不育患者血清抗精子抗体定量测定分析  

Evaluation of antisperm antibodies detection in infertile men with chronic prostatitis

作　　者：郑哲明[1] 郁兆存[1] 黄志宏[2] 邢发枢[1] 陈早庆[1] 黄华生[1] 方钟进[1] 杨昌俊[1] 

机构地区：[1]广东医学院附属东莞市厚街医院泌尿外科,广东东莞523945 [2]广东医学院附属东莞市厚街医院检验科,广东东莞523945

出　　处：《中国医药导报》2011年第35期49-50,共2页China Medical Herald

基　　金：广东省东莞市科技局课题(项目编号:201010515000148)

摘　　要：目的:探讨慢性前列腺炎并不育患者血清抗精子抗体与不育的关系,为临床治疗提供依据。方法:采用酶联免疫吸附法(ELISA)检测80例慢性前列腺炎并不育患者(A组)血清抗精子抗体(AsAb),同时选择正常生育的慢性前列腺炎患者50例(B组)作对照。结果:A组80例,检出AsAb阳性37例,阳性率46.3%,抗精子总抗体(T-Ig)(126.25±45.47)U/ml,B组AsAb阳性6例,阳性率12.0%,T-Ig(41.25±14.20)U/ml,两组阳性率及抗精子总抗体比较,差异均有统计学意义(均P<0.05)。结论:慢性前列腺炎并不育患者存在免疫性因素,ELISA方法敏感度高,操作简便,对临床合并前列腺炎的不育患者探求病因提供指导。Objective： To investigate the relationship between antisperm antibody（AsAb） and infertility men with prostatitis,and to provide some clue for clinic.Methods： Antisperm antibodies for infertile men with chronic prostatitis（n=80,group A） and fertile men with chronic prostatitis（n=50,group B） as control were respectively detected by the ELISA method.Results： The antisperm antibody was（126.25±45.47） U/ml in group A and（41.25±14.20） U/ml in group B,and the positive rate was 46.3% and 12.0% respectively,and there were significantly differences between two groups（all P 0.05）.Conclusion： Infertile men with chronic prostatitis can be relate to sperm autoimmunity,ELISA method is a highly sensitive and easy experiment method,which can explore the cause of unknown infertility and provide the guidance of clinical treatment and prognosis.

关 键 词：前列腺炎 男性不育症 抗精子抗体 酶联免疫吸附法 

分 类 号：R697.33[医药卫生—泌尿科学]