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作 者:张春华
出 处:《中国医药导报》2011年第35期178-179,共2页China Medical Herald
摘 要:目的:探讨多囊卵巢综合征(PCOS)患者不同的体重指数与脂质代谢的相关性。方法:收集门诊患者病历资料,按照PCOS诊断标准及体重指数(BMI)分为正常对照组30例、PCOS患者非肥胖组(non-fat group)39例与PCOS患者肥胖组(fat group)31例。三组分别检测空腹高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及三酰甘油(TG)血清值。结果:HDL-C在3组的血清值分别为(1.53±0.23)、(1.47±0.41)、(1.22±0.20)mmol/L。经统计学分析对照组与PCOS非肥胖组血清比较,差异无统计学意义(P=0.572);PCOS肥胖组HDL-C值高于对照组及非肥胖组血清值(P=0.004、0.008);PCOS肥胖组与非肥胖组在LDL-C与TG血清值上比较,两组间差异均无统计学意义(P=0.637、0.588)。结论:HDL-C血清水平可能与PCOS的病情程度有相关性。Objective: To explore the correlation between polycystic ovarian syndrome(PCOS) patients′different body mass index and lipid metabolism of relevancy.Methods: Service medical records from outpatient were collected and divided into control group(30 cases),PCOS patients of non-fat group(39 cases) and PCOS patients of fat group(31 cases) in accordance with PCOS diagnostic criteria and body mass index(BMI).High-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and triglycerides(TG) serum values were tested in three groups in fasting plasma.Results: Serum levels of HDL-C in three groups were(1.53±0.23),(1.47±0.41),(1.22±0.20)mmol/L;by statistical analysis,there was no statistically significant difference between PCOS patients of non-fat group and control group(P=0.572);serum levels of HDL-C in PCOS patients of fat group were more that in the control group and PCOS patients of non-fat group(P=0.004,0.008);serum levels of LDL-C and TG between PCOS patients of non-fat group and PCOS patients of fat group were no obvious difference(P=0.637,0.588).Conclusion: The serum levels of HDL-C may be having a correlation with PCOS illness extent.
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