CO2-Triggered Metal Catalyst- and Solvent-free Aminochlorination of Methylenecyclopropanes  

作　　者：齐明辉 邵黎雄 施敏 

机构地区：[1]Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science ＆ Technology, Shanghai 200237, China [2]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2011年第12期2739-2743,共5页中国化学（英文版）

基　　金：Project supported by Shanghai Municipal Committee of Science and Technology （No. 08dj1400100-2）, National Basic Research Program of China （973） （No. 2009CB825300） and the National Natural Science Foundation of China （Nos. 21072206, 20472096, 20872162, 20672127, 20821002 and 20732008）.

摘　　要：Aminochlorination of methylenecyclopropanes （MCPs） 1 can be achieved under CO2 atmosphere using N,N-dichlorotoluenesulfonamine （TsNCl2） as the nitrogen and halogen sources at room temperature to give the corresponding normal ring-remaining aminochlorinated products 2 along with/without the ring-opened aminochlorinated products 3 in moderate to good total yields. The present process takes the advantage of the green benign reaction conditions in the absence of any metal catalyst and solvent.Aminochlorination of methylenecyclopropanes （MCPs） 1 can be achieved under CO2 atmosphere using N,N-dichlorotoluenesulfonamine （TsNCl2） as the nitrogen and halogen sources at room temperature to give the corresponding normal ring-remaining aminochlorinated products 2 along with/without the ring-opened aminochlorinated products 3 in moderate to good total yields. The present process takes the advantage of the green benign reaction conditions in the absence of any metal catalyst and solvent.

关 键 词：aminochlorination METHYLENECYCLOPROPANES carbon dioxide 

分 类 号：TQ426.8[化学工程] TQ116.3