72例慢性HBV携带者肝穿结果分析  

Liver Biopsy in 72 Patients with Chronic Hepatitis B

作　　者：郭健苗[1] 张水木[1] 罗洽[1] 欧阳小予[1] 陈伟[1] 李华英[1] 

机构地区：[1]福建医科大学临床教学专业基地福建省三明市第二医院消化内科,366000

出　　处：《中华全科医学》2011年第12期1880-1881,共2页Chinese Journal of General Practice

摘　　要：目的了解慢性乙肝病毒(HBV)携带者病人肝穿病理及其与患者年龄、性别的关系。方法 72例慢性HBV携带者接受快速经皮肝穿刺及病理检查,肝组织切片由病理科医师盲法进行读片,分析肝脏炎症活动度、纤维化程度与其年龄、性别的关系。结果大部分慢性HBV携带者均有轻重不等的炎症及纤维化,轻度慢性肝炎(G1-2,S0-2)共38例,占52.78%,中度慢性肝炎(G3,S1-3)共25例,占34.72%,重度慢性肝炎(G4,S2-4)共5例,占6.94%,其中肝硬化2例。统计学分析发现:年龄、性别与肝脏炎症活动度、纤维化程度呈正相关。结论大部分慢性HBV携带者均有轻重不等的炎症及纤维化,对慢性HBV携带者,特别是高龄、男性患者,应予肝穿肝组织活检以判断其炎症活动度及纤维化程度,以判断是否采取抗病毒治疗等措施,延缓疾病进展。Objective To study the liver tissue pathology in chronic hepatitis B virus（HBV） carriers and it＇s association of the age and sex of patients.Methods Seven two of chronic HBV carriers accepted percutaneous liver biopsy,and the tissue slices were analyzed by the pathologist.Then the relationships between the degree of hepatic inflammation and liver fibrosis to the age and sex of patients were analyzed.Results Most of the chronic HBV carriers appeared inflammation and fibrosis：mild chronic hepatitis（G1-2,S0-2） was 38 cases（52.78%）,moderate chronic hepatitis（G3,S1-3） was 25 cases（34.72%）,severe chronic hepatitis（G4,S2-4） was 5 cases（6.94%）,and liver cirrhosis 2 cases.The age and sex of patients were positively related to the hepatic inflammation degree and fibrosis stage.Conclusion Chronic HBV carriers especially in the elderly and male patients should be given percutaneous biopsy to decide whether they should take antiretroviral therapy.

关 键 词：慢性HBV携带者 肝活检 肝活检组织学 

分 类 号：R512.6[医药卫生—内科学]