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出 处:《中华全科医学》2011年第12期1885-1885,1936,共2页Chinese Journal of General Practice
摘 要:目的探讨缩宫素在剖宫产手术中不同给药方式对产妇循环功能的影响。方法研究1组于患者术中胎儿娩出后立即给予静脉注射缩宫素,剂量为10 U;研究2组患者推注方法、时间与1组相同,剂量改为20 U;对照组不予缩宫素注射。记录舒张压(DBP)、收缩压(SBP)、心率(HR)、血氧饱和度(SPO2)各时期变化值。结果对照组患者血压和心率始终处于稳定状态,各检测阶段比较差异无统计学意义(P>0.05);研究1组、2组患者于缩宫素注射后2 min血压明显下降、心率明显上升,与同时期对照组比较差异具有统计学意义(P<0.05),持续10 min后才逐渐恢复正常。三组患者各时期比较血氧饱和度差异无统计学意义(P>0.05)。研究1组、2组应用缩宫素产妇产后出血量明显低于对照组(P<0.05)。结论缩宫素在剖宫产术中对于产妇循环功能短期内具有极明显的影响,可降低血压、升高心率,但对血氧饱和度无影响。Objective To discuss the impact of method of oxytocin administration on maternal circulation in puerpera undergoing cesarean section.Methods The oxytocin was given by intravenous bolus injection to the women of study group 1(10 units) and study group 2(20 units) immediately after the baby was delivered,but not to the control group.The changes of DBP,SBP,HR and SPO2 in different stages were recorded.Results The blood pressure and heart rate of control group of different detection stages were always in steady state(P0.05).The blood pressure significantly decreased and heart rate increased in study group 1 and 2 two minutes after the oxytocin injection,which was significant different as compared to the control group in the same period(P0.05).The volume of postpartum hemorrhage in study group 1 and 2 were significantly lower than that in the control group(P0.05).Conclusion Oxytocin has a significant short-term impact on the maternal circulation in cesarean section.It can decrease the blood pressure and increase heart rate,but not change SPO2.
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