驻岛官兵守礁前后淋巴细胞亚群的变化  

Changes of Lymphocyte Subpopulations in Soldiers from South China Sea Islands

作　　者：樊龙中[1] 李裕标[1] 周赤龙[1] 何俐勇[1] 王萍[1] 谭燮伦[1] 陈正[1] 仇建国[1] 刘俊[1] 

机构地区：[1]中国人民解放军422医院检验科,广东省湛江市524005

出　　处：《中华全科医学》2011年第12期1957-1957,1965,共2页Chinese Journal of General Practice

摘　　要：目的探讨南海驻岛礁官兵守礁前后淋巴细胞亚群的变化,探讨免疫功能改变的因果,如何进行改善,为守礁部队预防保健工作提供理论依据。方法采用美国BD FACSAria流式细胞仪检测守礁官兵守礁前后淋巴细胞亚群(CD3+、CD4+,CD8+、CD19+、CD16+CD56+)百分率。结果南海官兵淋巴细胞亚群CD3+、CD4+、CD8+,CD19+,CD16+CD56+守礁前百分率分别为(59.32±8.48)%,(38.67±3.17)%,(20.31±4.32)%,(10.27±1.64)%,(14.37±5.89)%。守礁后百分率分别为(55.17±9.16)%,(34.73±4.64)%,(26.56±3.66)%,(13.63±2.73)%;守礁前后CD4+/CD8+比值分别为1.90±0.11,1.31±0.17。与守礁前相比,守礁后官兵淋巴细胞亚群CD3+,CD4+,CD16+CD56+,CD4+/CD8+显著降低(P<0.01,P<0.05),CD19+,CD8+明显升高(P<0.05)。结论驻岛官兵守礁期间部分免疫功能发生改变,与官兵的心理应激能力和适应能力,心理状态,长时间日照和仪器辐射,高温高湿等恶劣生活条件,初次接触异样微生物、海洋生物、空气离子有关。Objective To investigate the changes of lymphocyte subpopulation and immunologic functions in soldiers from the South China Sea islands,and discuss the available treatment measures to provide a scientific evidence for the health protection of soldiers.Methods The percentage rate of lymphocyte subpopulation（CD3＋、CD4＋、CD8＋,CD19＋,CD16＋CD56＋） was tested by FACSAria flow cytometer among the solders from the South China Sea islands.Results Before they stationed on the islands,the percentage of CD3＋、CD4＋、CD8＋,CD19＋ and CD16＋CD56＋ were（59.32±8.48）%,（38.67±3.17）%,（20.31±4.32）%,（10.27±1.64）% and（14.37±5.89）%,respectively;the ratio of CD4＋ and CD8＋ was 1.90±0.11.After they accomplished the task,the percentage were（55.17±9.16）%,（34.73±4.64）%,（26.56±3.66）% and（13.63±2.73）%,respectively;the ratio of CD4＋ and CD8＋ was 1.31±0.17.The lymphocyte subpopulation of CD3＋,CD4＋,CD16＋CD56＋,CD4＋/CD8＋ had a significant reduction（P0.01 or P0.05） and the lymphocyte subpopulation of CD19＋,CD8＋ showed a significant rise（P0.05）.Conclusion The changes of immunologic function of soldiers from the islands are concerned with the ability to cope with stress,adaptive faculty,psychology state and bad living conditions.

关 键 词：南海驻岛官兵 淋巴细胞亚群 流式细胞术 

分 类 号：R446.113[医药卫生—诊断学]