早产儿神经心理发育23例1年随访观察  

One Year Follow-up of 23 Preterm Infants on the Observation of Neurodevelopment

作　　者：丁瑛雪[1] 杨丽君[1] 姚艳青[1] 崔红[1] 

机构地区：[1]首都医科大学附属北京友谊医院 儿科,北京100053

出　　处：《中国医刊》2011年第12期42-44,共3页Chinese Journal of Medicine

基　　金：国家自然科学基金(30872778/C1704);北京市自然基金(NO.7072023)

摘　　要：目的评估早产儿随访到1岁时的神经心理发育。方法对2008年1月至2009年12月收治并存活出院的孕周小于37周的早产儿,分为两组,胎龄<34周组和≥34周组,于校正胎龄1岁时进行回顾性分析,并与同期住院并坚持随访至1岁的足月儿进行比较。结果 1岁时早产儿神经心理发育的5个方面均低于足月儿,差异有统计学意义;早产胎龄对9月龄时神经心理发育的影响:胎龄<34周和≥34周的两组有明显差异,而到1岁时这种差别明显减少。9月龄时血红蛋白水平(以110g/L为界限)对早产儿神经心理发育有明显差异,主要表现在适应性、精细运动、语言方面;直到1岁时这种差异消失。结论校正胎龄1岁时早产儿神经心理发育低于足月儿,血红蛋白水平可影响早产儿的神经心理发育。Objective To assess the neurodevelopment of preterm infants at 1-year-old based on corrected gestational age. Methods All infants admitted in our hospital from Jan in 2008 to Dec in 2009 were divided into two groups according to gestational age, group 1 ： born 〈 34 completed gestational weeks; group 2： born.after 34 completed gestational weeks. Information at 12 months corrected age about neurodevelopment was respectively analyzed and compared with normal full term infants who admitted at the same period and followed up to 1 year old. Results It is sig- nificance between term infants and preterm infants on neurodevelopment at 12 months corrected age; gestational age more than 34 weeks is much better development than that of gestational age less than 34 weeks at 9 months corrected age, but the difference disappears at 12 months;the same change can be seen in the level of HGB. Conclusions This study gives estimates for neurodevelopment at 12 months corrected age for preterm infants. Gestational age and nutrition are the same important for the neurodevelopment of pretern infants.

关 键 词：早产儿 神经心理发育 随访 

分 类 号：R722.6[医药卫生—儿科]