超高效液相色谱-串联质谱法测定纺织品中致癌性染料  

UHPLC-MS/MS Determination of Carcinogenic Dyestuffs in Textiles

作　　者：吕刚[1] 冯智劼[1] 曹丽静[1] 张彬[1] 张占明[1] 

机构地区：[1]天津出入境检验检疫局,天津300201

出　　处：《理化检验（化学分册）》2011年第11期1310-1312,1315,共4页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家质量监督检验检疫总局计划项目(2008IK182)

摘　　要：分别采用快速溶剂萃取法(ASE)和汗渍模拟液萃取法(SSE)萃取纺织品中11种致癌性染料,采用超高效液相色谱-串联质谱法测定萃取液中其含量。在色谱分离中选用HypersilGold色谱柱,并用pH 7.5的磷酸二氢四丁基铵和乙腈按不同比例混合的流动相进行梯度淋洗。质谱测定中采用电喷雾正离子和负离子模式离子化、多反应监测模式测定11种致癌性染料,外标法定量。11种致癌性染料在1.0～1 000μg.L-1内呈线性,检出限(3S/N)在0.5～30.0μg.L-1之间。快速溶剂萃取法处理所得11种致癌性染料的回收率在9.12%～102.4%之间,而汗渍模拟液法所得的回收率在0.72%～2.18%之间。Samples of textile were treated by the accelerated solvent extraction（ASE） and sweat simulant extraction（SSE）,to separate 11 carcinogenic dyestuffs and their contents in the extract were determined by UHPLC-MS/MS.For separation of the dyestuffs,Hypersil Gold chromatographic column was used as stationary phase,and mixtures of tetrabutyl ammonium dihydrogen phosphate solution of pH 7.5 and acetonitrile in different ratios were used as mobile phase in the gradient elution.The ionization modes of ESI＋ and ESI-with MRM mode of detection were adopted in MS/MS determination,with quantification by external standard method.Linearity ranges of the 11 dyestuffs were kept same from 1.0 to 1 000 μg·L-1 with detection limits（3S/N） in the range of 0.5-30.0 μg·L-1.Values of recovery of the 11 dyestuffs were in the range of 9.12%-102.4% obtained by ASE and in the range of 0.72%-2.18% obtained by SSE.

关 键 词：超高效液相色谱-串联质谱法 纺织品 致癌性染料 

分 类 号：O657.63[理学—分析化学]