气相色谱法测定细辛挥发油中甲基丁香酚和黄樟醚的含量  

Quantitative determination of methyleugenol and safrole in Herba Asari by gas chromatography

作　　者：周长征[1] 杨春澍[1] 马长华[1] 王嘉琳 

机构地区：[1]北京中医药大学中药学院,北京100029

出　　处：《中国药学杂志》1999年第12期836-839,共4页Chinese Pharmaceutical Journal

摘　　要：目的：探讨正品细辛与非正品细辛、细辛地上部分与地下部分及正品细辛间挥发油中主成分含量的差异，为建立中药细辛的质量评价体系提供资料。方法：首次用内标法对国产药用细辛１２ 个种共２４ 个样品挥发油中甲基丁香酚（ｍｅｔｈｙｌｅｕｇｅｎｏｌ）和黄樟醚（ｓａｆｒｏｌｅ） 的含量进行了气相色谱分析。结果与结论：正品细辛中甲基丁香酚和黄樟醚的含量远高于非正品细辛；正品细辛地下部分和地上部分挥发油中两种成分的含量差异不大；三种正品细辛的挥发油中甲基丁香酚的含量依次为汉城细辛＞ 北细辛＞ 华细辛，黄樟醚的含量依次为华细辛＞ 北细辛＞OBJECTIVE: To quantitatively analyze methyleugenol and safrole in Herba Asari by GC METHODS: The gas chromatographic conditions included column SE 54, supporting gas of N 2 and FID detector The internal standard was n tetradecane RESULTS and CONCLUSION: The content of methyleugenol and safrole in Sect Asiasarum was far more than that in other sections; There wasn′t evident difference in the content of these two compound between the upterranean part and the subterranean part In the case of Sect Asiasarum , the content of methyleugenol decreased in the following order: Asarum sieboldii f seoulense>A heterotropoides var mandshuricum>A sieboldii On the other hand, the content of safrole decrease in the following order: A sieboldii>A heterotropoides var mandshuricum>A sieboldii f seoulense

关 键 词：细辛 甲基丁香酚 黄樟醚 气相色谱 中药 

分 类 号：R282.71[医药卫生—中药学] R284.1[医药卫生—中医学]