用放射性肾图检测74例SLE患者肾脏损害  

Detection of the renal damage in 74 cases with SLE by radioistope renogram

作　　者：周晓鸿[1] 张佩莲[1] 王万里[1] 谢红[1] 冒长峙[1] 

机构地区：[1]昆明医学院第二附属医院皮肤科,云南昆明650101

出　　处：《皮肤病与性病》1999年第4期3-4,共2页Dermatology and Venereology

摘　　要：目的 :探讨SLE患者肾功损害的敏感指标及肾小管损害的检测方法。方法 :用131Ⅰ作为示踪剂对 74例SLE患者的 14 8个肾脏进行肾图描记及定量指标分析。结果 :异常肾图 79个 (5 3 4 % )。半排时间、 15分钟残留率的异常率分别为 5 1 3 %及 3 8 5 % ,74例中肾脏指数和 /或分浓缩率异常 2 8人 (3 7 8% ) ,较尿素氮和 /或及肌酐异常者(共 9人 ,12 2 % )高。结论 :肾图检测可提高对肾脏损害判断的敏感性 ,并可检测SLE患者的肾小管损害。。To investigate the sensitive method for diagosing early renal damage and damge of the renal tubule.we use radioisotope renogram with I 131 as tracer to draw the renogram and to examine the quantitative idexes.There were 79(53 4%)abnormal renogram.After quantitative analysis of renogram,the abnormal rate of halfclearance(TC 1/2 ) and 15-minute residual ratio(C15/b)were 51 3% and 38 5% respectively.The abnormal rate(37 8%)of renal index(RI)and/or MCR,was much higher than that(12 2%)of nitrogen(BUN)and/or creatinine(Cr).Conclusion The results suggest that the radioisotope renogram are more sensitive in detecting renal damage than that of BUN and/or Cr,and can detect the damgae of the renal tubule simultaneously.

关 键 词：SLE 肾图 检测 肾脏损害 

分 类 号：R593.241[医药卫生—内科学]