对甲酚与邻甲酚对斑马鱼的联合毒性研究  

Joint Toxicity of P-Cresol and O-cresol to Zebrafish(Brachydanio rerio)

作　　者：房妮[1] 张松林[2] 俱国鹏[1] 

机构地区：[1]陕西省灾害监测与机理模拟重点实验室宝鸡文理学院,陕西宝鸡721007 [2]西北师范大学地理与环境科学学院,甘肃兰州730070

出　　处：《江西农业学报》2011年第11期156-158,共3页Acta Agriculturae Jiangxi

基　　金：甘肃省教育厅基金项目(0801-08);甘肃省自然科学基金(2007GS03614);甘肃省重点学科生态经济学;自然地理学资助项目;宝鸡文理学院重点科研项目(ZK08122)

摘　　要：以静水法测试了对甲酚与邻甲酚对斑马鱼的单一和联合急性毒性,并以毒性单位分析法和Marking相加指数法对其联合毒性效应类型进行了判定。试验结果表明,对甲酚和邻甲酚的单一毒性均为中毒,前者的毒性大于后者。Marking相加指数法和毒性单位分析法对两者的联合毒性作用的评价结论一致:等毒性配比下,对甲酚与邻甲酚的联合毒性在247、2和96 h均为协同作用,在48 h为相加作用。The single and joint acute toxicities of P-cresol and O-cresol to zebrafish（Brachydanio rerio） were examined by using the static water method,and the type of joint toxic effect was determined with the methods of toxic unit analysis（TU） and Marking＇s additive index（AI）.The results showed that the single acute toxicity of both P-cresol and O-cresol was moderate,and the toxicity of the former was greater than that of the latter.The joint toxicity assessment conclusions had no difference between TU method and AI method： under the condition of equal toxicity proportioning,the joint toxicity of P-cresol and O-cresol was synergistic at 24,72 and 96 h,and additive at 48 h.

关 键 词：对甲酚 邻甲酚 斑马鱼 联合毒性 

分 类 号：TQ450.26[化学工程—农药化工]