手术分娩对产妇和新生儿血中γδT细胞的影响  

Influence of operative delivery methods on γδT cells quantity in blood of parturient women and newborns

作　　者：王全英[1] 陈复兴[2] 徐德朋[3] 周忠海[2] 赵美玲[3] 

机构地区：[1]中国人民解放军第九七医院妇产科,徐州221004 [2]中国人民解放军第九七医院实验科,徐州221004 [3]中国人民解放军第九七医院麻醉科,徐州221004

出　　处：《山西医科大学学报》2011年第11期919-921,共3页Journal of Shanxi Medical University

摘　　要：目的探讨不同分娩方式对产妇和新生儿血中γδT细胞数量的影响。方法足月分娩产妇60例,依据分娩方式和手术时机分为自然分娩(NL)组、择期剖宫产(CS)组、急诊剖宫产(CS-E)组,各20例。分别采集分娩时的产妇外周血和新生儿脐血,采用流式细胞仪检测γδT细胞的百分数。结果 NL组、CS组、CS-E组γδT细胞百分数,在产妇血中分别为(11.19±8.99)%,(9.00±5.23)%,(11.98±5.24)%,各组间比较差异无统计学意义(P>0.05);在新生儿脐血中依次为(1.29±0.36)%,(4.67±3.47)%,(1.24±0.67)%,CS组显著性高于其他两组(P<0.01)。结论手术分娩对产妇血中γδT细胞影响不明显,择期剖宫产可致新生儿脐血中γδT细胞的增高。Objective To evaluate the influence of operative delivery methods on γδT cells quantity in blood of parturient women and newborns.Methods Sixty term parturients based on delivery method and operative time were divided into three groups：natural labor group（NL group,n=20）,periodic c-section group（CS group,n=20）,and emergency c-section group（CS-E group,n=20）.The peripheral blood and cord blood were collected from parturient women and newborns,respectively.The percentage of γδT cells in blood samples was detected by flow cytometry.Results The γδT cell percentage was（11.19±8.99）%,（9.00±5.23）%,（11.98±5.24）% in peripheral blood of parturient women in NL,CS,CS-E groups respectively,but there was no significant difference among 3 groups（P0.05）.The γδT cell percentage in cord blood of newborns in CS group was significantly higher than that in NL and CS-E groups [（4.67±3.47）% vs（1.29±0.36）%,（1.24±0.67）%,P0.01].Conclusion The operative delivery way may not have effect on blood γδT cell of parturient women.The periodic c-section may cause the growth of γδT cell in cord blood of newborn.

关 键 词：分娩 剖宫产手术 ΓΔT细胞 产妇 新生儿 

分 类 号：R392.12[医药卫生—免疫学]