金黄地鼠视皮层17、18区乙酰胆碱阳性神经元  

The Acetylcholine immunoreactive Neurons and Their Distribution in the Area 17 and 18 of the Visual Cortex of Hamster.

作　　者：李俊凤[1] 吴奇久[1] 

机构地区：[1]中国科学院生物物理研究所视觉信息加工开放研究实验室,北京100101

出　　处：《生物化学与生物物理进展》1999年第6期587-590,共4页Progress In Biochemistry and Biophysics

基　　金：中国科学院重大项目!(9002KP8524)

摘　　要：利用乙酰胆碱（ ａｃｅｔｙｌｃｈｏｌｉｎｅ， Ａｃｈ） 自身抗体对金黄地鼠视皮层１７、１８ 区乙酰胆碱阳性神经元及其分布进行免疫学显示并进行量化分析． 实验发现， Ａｃｈ 阳性细胞大部分为非锥体神经元， 也有少量锥体神经元． Ａｃｈ阳性神经元在视皮层的Ⅱ～Ⅵ层， 主要分布在Ⅱ～Ⅳ层． 在不同层次中其阳性神经元类型存在某些差异， Ⅱ～Ⅳ中双极细胞居多， 其他层次中多极细胞占优势．１７ 区的这类神经元数量较多且集中成垂直于皮层表面的细胞带，１８ 区的神经元数量相对较少且多呈分散状态．Acetylcholine localization was studied immunohistochemically in neurons of the area 17 and 18 in the hamster visual cortex using anti acetylcholine serum. It was found that the Ach labeled cells are nonpyramidal neurons primarily and a few pyramidal neurons also exist. These neurons were found to be distributed in layer Ⅱ～Ⅵ, concentrated in the layer Ⅱ～Ⅳ. The neurons in the area 17 having greater density are arranged to form a columns perpendicular to the surface of the visual cortex and the neurons in the area 18 having smaller density are distributed dispersely. In the different layers of the visual cortex, the type of stained neurons has variation with that the majority of these neurons were bipolar in layer Ⅱ, Ⅳ and the multipolar cells in the other layers.

关 键 词：视皮层 乙酰胆碱 免疫组织化学 神经元 数量分布 

分 类 号：Q436[生物学—生理学] R339.146[医药卫生—人体生理学]