钛表面超亲超疏性构筑及其对抗菌性影响  

Superhydrophilic/Superhydrophobic Surface Constructions on Titanium and Their Effects on Anti-bacterial Properties

作　　者：王国玮[1] 黄巧玲[1] 胡仁[1] 林昌健[1] 王浩[2] 张立海[2] 唐佩福[2] 

机构地区：[1]厦门大学固体表面物理化学国家重点实验室,化学化工学院化学系,福建厦门361005 [2]中国人民解放军总医院,北京100853

出　　处：《电化学》2011年第4期388-392,共5页Journal of Electrochemistry

基　　金：国家自然科学基金项目(20773100)资助

摘　　要：生物材料植入人体后若受到细菌感染就可能导致植入手术失败,因此植入材料的抗菌性研究具有重要的意义.由于内植物感染的第一步是细菌在材料表面的贴附,植入材料的表面性质对其抗菌性有决定性的影响.本文应用电化学法在钛表面构筑一层超亲水或超疏水的表面膜层,并由体外抗菌性试验研究材料表面的润湿性对细菌贴附的影响,以期借助改变材料表面的润湿性达到抗菌作用.结果表明,相比超亲水表面,超疏水表面上贴附的细菌数明显减少.The microbial infection of biomaterials often causes clinic problems and sometimes even leads to the prosthesis failure.It is,therefore,important to prevent the biomaterials from bacterial contamination.This can be done by using anti-bacteria drugs.However,this method causes physiological burdens to the patients and does not always work.To stop the contamination from the just beginning is believed to be a better choice.The first step for infection is the attachment of bacteria on the material.In this work,the thin TiO2 nanotubes array films we constructed with totally different wettabilities showing either superhydrophobic or superhydrophilic.The bacterial attachment behaviors on them were evaluated.It is shown that the numbers of viable colonies on the superhydrophobic film were significantly less than those on the superhydrophilic one.

关 键 词：TIO2 润湿性 抗菌性 

分 类 号：R318.08[医药卫生—生物医学工程]