加用β-七叶皂甙和复方甘油果糖治疗急性脑梗死临床观察  

Clinical Study of Aescin Combined with Glycerol-Fructose in Treatment of Acute Cerebral Infarction

作　　者：庹军[1] 

机构地区：[1]大邑县人民医院,四川成都611330

出　　处：《现代临床医学》2011年第6期425-426,共2页Journal of Modern Clinical Medicine

摘　　要：目的:观察加用β-七叶皂甙和复方甘油果糖治疗急性脑梗死的疗效及安全性。方法:将60例经头颅CT确诊的脑梗死患者随机分为2组,2组均给予溶栓、降颅压、神经细胞营养等常规治疗。在此基础上,观察组加用β-七叶皂甙和复方甘油果糖静脉滴注,对照组单用复方甘油果糖静脉滴注。连用10天,比较2组治疗前后神经功能缺损评分、脑梗死灶周围水肿消退情况及副作用。结果:观察组神经功能缺损评分明显低于对照组(P<0.05),脑梗死灶周围水肿消退明显快于对照组(P<0.05)。2组在治疗过程中均未观察到血尿、溶血、局部血管刺激征、静脉炎、肾功能损害等副作用。结论:加用β-七叶皂甙与复方甘油果糖治疗急性脑梗死安全有效,副作用少,值得临床推广。Objective：To investigate the efficacy and safety of aescin plus glycerol-fructose for acute cerebral infarction.Methods：60 patients with acute cerebral infarction diagnosed by brain CT were divided into two groups.All patients with acute cerebral infarction received conventional therapy.In addition,30 patients in trial group received intravenous infusion of aescin and glycerol-fructose for 10-day,30 patients in control group only received glycerol-fructose for 10 day.Neurologic impairment score,absorption state of cerebral edema were measured.Results：Compared to control group,patients＇ neurologic impairment scores were lower（P〈0.05）,absorption of cerebral edema was faster in trial group（P〈0.05） after treatment combined aescin with glycerol-fructose.No side effects were observed in both groups.Conclusion：Aescin plus glycerol-fructose are effective and safe and worthy of further application for acute cerebral infarction.

关 键 词：脑梗死 Β-七叶皂甙 甘油果糖 

分 类 号：R651.2[医药卫生—外科学]