大黄虫丸与丹参抗乙肝后肝纤维化的研究  

The Study of Salviae Miltiorrhizae and Dahuang Zhechang Wan Anti hepatic Fibrosis of Post hepatitis B

作　　者：吴广利[1] 许春华[1] 陈传福[1] 王连文[1] 牟卫平[1] 

机构地区：[1]滨州医学院附属医院,256603

出　　处：《山东医药》1999年第22期5-6,共2页Shandong Medical Journal

基　　金：山东省卫生厅青年科研基金

摘　　要：观察丹参、大黄虫丸单用或联合用对乙肝后肝纤维化的疗效。结果显示 ,大多数患者经治疗后血清透明质酸 ( HA)、层粘连蛋白 ( LN)和 型胶原 ( · C)有不同程度的下降 ,以联用组下降更明显 ( P<0 .0 1)。认为丹参与大黄虫丸二者联用疗效更好。To select effective drugs of anti hepatic fibrosis of post hepatitis B,the serum parameters of hepatic fibrosis (HA.LN.Ⅳ.C)were determined in patients of hepatic fibrosis before and after treated with salviae miltiorrhizae or Dahuang Zhechong Wan or both,with randonized,double blind and controlled trial.Except Ⅳ.C in saliviae miltiorrhizae group,the serum levels of HA LN Ⅳ.C were decreased in three groups after treatment,respectively There are markedly difference between cotreatment group and two other groups (P<0 01).The results indicated that salviae mitiorrhizae or Dahuang Zhechong Wan alone and both used to treat hepatic fibrosis could regarded as an effective antifibrotic drugs.

关 键 词：肝纤维化 丹参 大黄Zhe虫丸 乙型肝炎 

分 类 号：R259.126.2[医药卫生—中西医结合] R259.752[医药卫生—中医内科学]