胃炎方为主治疗胃癌前病变的临床研究  

Clinical Study of Modified “Gastritis Formula” for Treatment of Pre carcinomatous States of Stomach (Chronic Gastritis)

作　　者：方雅君[1] 杨炳初[1] 

机构地区：[1]上海市第六人民医院,200233

出　　处：《中成药》1999年第12期633-635,共3页Chinese Traditional Patent Medicine

摘　　要：目的：用改进胃炎方治疗胃癌前的临床观察。方法：用自拟胃炎方（ 黄芪、当归、丹参、白芍、蒲公英、黄连、莪术、徐长卿） ，对１０４ 例慢性萎缩性胃炎，伴有肠腺上皮化生，不典型增生等胃癌前状态病例，经３ ～６ 个月的治疗观察。结果：症状有效率９５ ．１９ ％ ，胃镜及病理显效４７ 例，有效３８例，无效１９ 例，病理总有效率８１ ．７ ％ ，其中胃粘膜病理疗效分别为：腺体萎缩治疗有效率７１ ．７９ ％ ；肠腺上皮化生治疗有效率７８．２６ ％ ；不典型增生治疗有效率８９ ．７４ ％ 。Objective: To study the treatment of pre carcinematous states of stomach. Methods: 104 cases of pre carcinomatous states of stomach (chronic atrophic gastritis in association with intestinal metaplastia and atypical proliferation) were treated by modified “gastritis formula” (composed of Radix Astragali, Radix Angelicae Scinensis, Radix Salviae Miltiorrhizae Miltiorrhizae, Radix Paeoniae Alba, Herba Taraxaci, Rhizoma Coptidis, Rhizoma Coptidis, Rhizoma Zedoariae and Radix Cynanchi Paniculati). Results: After application of the formula for 3～6 months the results showed pathologic remarkable effectiveness in 47 cases (45.2%), effectiveness in 38 cases (36.5%) and total effective rate of 81.7%. The change of pathologic morphology with glandular atrophy in 78 cases, effective rate 71.7%; with intestinal metaplastia in 92 cases, effective rate 78.2%; with atypical proliferation in 39 cases, effective rate 89.7%. Conclusion: The use of formula obtains better clinical effect.

关 键 词：胃炎方 癌前病变 胃肿瘤 中医药疗法 

分 类 号：R273.520.5[医药卫生—中西医结合]