冠心病患者血清超敏C-反应蛋白检测的分析  

Analysis of Serum High Sensitive C-reactive Protein Detection in Patients with Coronary Heart Disease

作　　者：金明林[1] 李丹妮[1] 黎明新[2] 

机构地区：[1]沈阳医学院基础医学院生物化学教研室,辽宁沈阳110034 [2]沈阳医学院奉天医院检验科

出　　处：《沈阳医学院学报》2011年第4期216-217,共2页Journal of Shenyang Medical College

摘　　要：目的:探讨超敏C-反应蛋白(high sensitive C-reactive protein,hs-CRP)与冠心病(coronary heart disease,CHD)的关系。方法:选沈阳医学院奉天医院CHD患者76例为病例组[稳定型心绞痛(stable angina pectoris,SAP)25例,不稳定型心绞痛(unstable angina pectoris,UAP)4l例,急性心肌梗死(acute myocardial infarction,AMI)10例]和50例健康体检者为对照组,分别以免疫比浊法测定其hs-CRP值,并统计分析。结果:CHD组hs-CRP值均明显高于对照组,差异有统计学意义(P<0.01)。UAP组和AMI组hs-CRP值均高于SAP组,而AMI组hs-CRP值又高于UAP组,差异具有统计学意义(P<0.05)。结论:CHD患者依病情发展情况的不同,hs-CRP的增高程度亦不同,提示hs-CRP与CHD患者病情发展存在密切的关系,可为CHD患者诊断及疗效观察提供参考依据。Objective：To explore the relationship between high sensitive C-reactive protein（hs-CRP） and coronary heart disease（CHD）.Method：There were totally 76 patients with CHD enrolled in Fengtian hospital as CHD group,25 cases with stable angina pectoris（SAP）,4l cases with unstable angina pectoris（UAP）,10 cases with acute myocardial infarction（AMI）were included and 50 healthy adults as control group.The hs-CRP were detected and analyzed in both of the groups.Results：There were significant differences between CHD group and control group in serum levels of hs-CRP（P0.01）.The level of serum hs-CRP in patients with UAP and AMI were higher than that of patients with SAP and the AMI groups were higher than that of UAP groups（P0.05）.Conclusion：According to different development condition in patients with CHD,the degree of higher hs-CRP was different.It prompted that there is a close relationship between hs-CRP and the progression of CHD.The hs-CRP can provide references for the clinical diagnosis and clinical observation of CHD.

关 键 词：超敏C-反应蛋白 冠心病 急性心肌梗死 

分 类 号：R541.4[医药卫生—心血管疾病]