脾虚证胃粘膜组织细胞病理学研究  

Histocytopathological Study on Gastric Mucosa of Spleen Deficiency Syndrome

作　　者：尹光耀[1] 张武宁[2] 何雪芬[1] 陈一[2] 尹玉芬[1] 沈小静[1] 

机构地区：[1]江苏省无锡市第三人民医院,江苏214041 [2]复旦大学国家微分析中心

出　　处：《中国中西医结合杂志》1999年第11期660-663,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的:探索脾虚证胃粘膜相、胃粘膜病变的程度与脾虚证型的关系。方法:取经检测排除心、肺、肝、胆、胰、肾及肠等器质性疾病的188例脾虚证患者胃粘膜,应用光学显微镜、扫描电镜、透射电镜和组织化学染色,进行组织病理学、亚细胞超微结构检测。结果:脾气虚证和脾阳虚证胃粘膜既可有器质性病变存在(G型),也可无器质性病变存在(F型);脾阴虚证和脾虚气滞证胃粘膜均有器质性病变存在,且病变程度也较G脾气虚证与G脾阳虚证为重(P<005～001)。结论:脾虚证未必都有胃粘膜病变,病变的程度与脾虚证型的演化互为因果。To explore the pictures of gastric mucosa of Spleen deficiency syndrome, and the relationship between the degree of pathological changes of gastric mucosa and types of Spleen deficiency syndrome. Methods: One hundred and eighty eight Spleen deficiency patients with organic diseases of heart, lung, liver, gallbladder, pancreas, intestine and kidney excluded were examined their gastric mucosa. Tests of histopathology and subcellular ultrastructure were conducted by using optical microscope, electron scanning microscope, electron transmission microscope and histochemical staining methods. Results: The gastric mucosa of Spleen Qi deficiency and Spleen Yang deficiency patients could either be affected with organic lesion (type G) or unaffected (type F); the gastric mucosa of Spleen Yin deficiency and Spleen deficiency with Qi stagnation were both affected by gastric lesions, and the degree of their lesions was more serious than that of Spleen Qi deficiency of type G and Spleen Yang deficiency of type G, P<0 05～0 01. Conclusion: Pathological changes did not necessarily occur in the gastric mucosa of Spleen deficiency patients; the degree of pathological changes was relevant with the evolution of Spleen deficiency types.

关 键 词：脾虚证 胃粘膜背景病变 上皮细胞核 线粒体 

分 类 号：R256.302[医药卫生—中医内科学]