阻塞性睡眠呼吸暂停低通气综合征患者上呼吸道形态影像学研究  

320CT imaging of upper airway structure of the patients with obstructive sleep apnea hypopnea syndrome

作　　者：应彬彬[1] 叶贤旺[1] 傅卜年[1] 黄依琴[1] 黄求理[1] 李哲光[1] 

机构地区：[1]宁波市第一医院,宁波315010

出　　处：《现代实用医学》2011年第10期1097-1099,共3页Modern Practical Medicine

基　　金：宁波市医学科技计划项目(2009A12)

摘　　要：目的通过320排多层螺旋CT(简称320CT)对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者上呼吸道形态的影像学研究,探讨OSAHS的发病机制。方法收集14例经多导睡眠监测仪诊断为OSAHS的患者和7例正常志愿者为研究对象,采用320CT对所有受试者分别在4个时相下进行上气道连续扫描并重建,范围从硬腭到声门。这4个时相分别为平静呼吸、深吸气末、深呼气末及闭口堵鼻深吸气(Müller)动作。运用平面重建软件分别对上气道进行横断、矢状及冠状面的重建并测量鼻咽部、口咽部、喉咽部的截面积。所将得数据进行统计学分析。结果 OSAHS组腭后区截面积在4个时相中均小于对照组,差异均有统计学意义(均<0.05)。舌后区截面积在吸气相及Müller动作相中小于对照组,差异均有统计学意义(均<0.05)。鼻咽部及喉咽部的截面积差异均无统计学意义(均>0.05)。结论口咽区是OSAHS患者上呼吸道狭窄的主要区域;运用320 CT检测上呼吸道对于OSAHS的诊治具有较高的参考价值。Objective To study the upper airway characteristics of obstructive sleep apnea hypopnea syndrome（OSA-HS） with 320CT and the mechanism of OSAHS.Methods The upper airway of 14 OSAHS patients and seven controls were scanned by 320CT at the time of deep inspiration,deep expiration,normal respiration and Müller action.The cross section areas of upper airway at naso-pharyngeal,velo-pharyngeal and tongue-pharyngeal were measured and compared.Results Mean cross section areas of velo-pharyngeal in OSAHS were less than those in the control group at the time of deep inspiration,deep expiration,normal respiration and Müller action（P〈0.05）.Mean cross section areas of tongue-phar-yngeal in OSAHS were less than those in the control group at the time of deep inspiration and Müller action（P〈0.05）.Con-clusions Oropharynx region is the main obstructive regions for OSAHS,and 320CT has significant diagnostic value for OSAHS

关 键 词：体层摄影术 X线计算机 阻塞性睡眠呼吸暂停 上呼吸道 

分 类 号：R445.3[医药卫生—影像医学与核医学]