MR扩散加权与BLADE-T2-SPAIR对肝脏局灶性病变检出的比较研究  

Detection of focal liver lesions:comparison of DWI and BLADE-T2-SPAIR sequence

作　　者：李瑞利[1] 赵晶[1] 元达[1] 李宏军[1] 

机构地区：[1]首都医科大学附属北京佑安医院放射科,北京100069

出　　处：《磁共振成像》2011年第6期403-407,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：北京卫生系统高层次卫生技术人才培养计划项目(编号:2009-3-55)资助

摘　　要：目的比较磁共振扩散加权成像(diffusion-weighted imaging,DWI)与刀锋伪影校正(BLADE)技术、精确频率反转恢复(spectral presaturation attenuated inversion recovery,SPAIR)T2压脂序列对肝脏局灶性病变的检出效能。方法选择BLADE-T2-SPAIR与DWI2种序列均进行了检查的35例患者共51个病灶(31个恶性:肝细胞癌21个,转移瘤10个;20个良性:囊肿6个,血管瘤14个)纳入本次研究。1位读片者分别阅读T2压脂与DWI图像并测量病灶和邻近肝实质在DWI及T2压脂上的信号强度,计算病灶/肝信号强度比(contrast ratios,CR)。比较2种序列之间检出率及CR值的差异。结果 2种序列对囊肿、血管瘤、转移瘤的检出率之间的差异无统计学意义,T2压脂序列对肝细胞癌的检出率高于DWI(P<0.05)。所有病灶均测量了CR,囊肿的CR值在T2WI高于DWI(P<0.05),血管瘤、肝细胞癌、转移瘤的CR值在2种序列之间的差异无统计学意义。结论 DWI对肝细胞癌的检出效能低于T2压脂序列。Objective： To compare the efficacy of DWI and BLADE-T2-SPAIR in detection of focal liver lesions. Materials and Methods： Thirty-five patients with 51 focal hepatic lesions （31 malignant and 20 benign） were included in the study. Both BLADE-T2-SPAIR and DWI were performed on each patient. One radiologist interpreted BLADE-T2-SPAIR and DWI images and measured the signal intensity （SI） of the lesions and adjacent liver parenchyma on BLADE-T2-SPAIR and DWI, and the contrast ratios （CR, the ratio of SI of lesion/liver） were calculated. The detecting rates of the lesions and the mean CRs were compared between the two sequences. Results： There were no significant difference in the detecting rate of cyst, hemangioma, metastatic tumor by BLADE-T2-SPAIR and DWI, the detecting rates of hepatocellular carcinoma （HCC） by BLADE-T2-SPAIR were higher （P0.05） than those by DWI. CR was calculated for all lesions. The CRs of cyst on BLADE-T2-SPAIR were higher than those on DWI （P0.05）, and no significant differences were found between the two sequences as for the CRs of hemangioma, HCC, metastatic tumor. Conclusions： DWI is not superior to T2WI in detection of HCC.

关 键 词：肝脏 肝脏局灶性病变 扩散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]