NSTEMI患者血清hs-CRP、cTnI和D-D检测的临床评价  

Clinical Evaluation of Changes of Serum hs-CRP,cTnI and D-D Levels in Patients with Non-ST-segment Elevation Myocardial Infarction(NSTEMI)

作　　者：张莉[1] 葛长江[1] 王刚[1] 

机构地区：[1]江苏省连云港市妇幼保健院,222000

出　　处：《放射免疫学杂志》2011年第6期678-680,共3页Journal of Radioimmanology

摘　　要：目的:探讨非ST抬高型急性心肌梗死(NSTEMI)患者血清hs-CRP、cTnI和D-D水平变化的临床意义。方法:应用免疫比浊法、生化法和酶联法对66例疑NSTEMI患者进行了血清hs-CRP、cTnI和D-D检测,并根据临床诊断分成观察组和对照组,进行统计学分析。结果:NSTEMI患者血清hs-CRP、cTnI和D-D水平均非常显著地高于对照组(P<0.01),且血清hs-CRP水平与cTnI和D-D水平呈显著的正相关(r=0.5782、0.6134,P<0.01)。结论:血清hs-CRP、cTnI和D-D水平升高与NSTEMI密切相关,对NSTEMI的预测、诊断和预后均有一定的临床价值。Objective To explore the significance of the changes of the levels of serum hs-CRP,cTnI and D-D in patients with non-ST-segment elevation myocardial infarction（NSTEMI）.Methods Serum hs-CRP（with immunoturbidimetry method）,serum cTnI（with Biochemistry）,serum D-D（with ELISA） levels were measured in 66 patients who were suspected NSTEMI.Comparative analysis of observation group and control group divided by clinical diagnosis was conducted.Result The levels of serum hs-CRP,cTnI and D-D were significantly higher than those in controls（P0.01）.The level of serum hs-CRP was obviously positive correlated with the levels of cTnI,D-D（r=0.5782,0.6134,P0.01）.Conclusions The changes of levels of serum hs-CRP,cTnI and D-D closely related to NSTEMI,and might be of clinical value of prediction,diagnosis and prognosis in patient with NSTEMI.

关 键 词：急性心肌梗死 非ST抬高型急性心肌梗死 超敏C反应蛋白 肌钙蛋白Ⅰ D-二聚体 

分 类 号：R541.4[医药卫生—心血管疾病]