催化山梨醇脱水制备异山梨醇的固体酸催化剂  

Dehydration of sorbitol to isosorbide on solid acid catalyst

作　　者：孙鹏[1] 耿红冉[2] 李正文[1] 张小伟[1] 余定华[1] 

机构地区：[1]南京工业大学生物与制药工程学院,南京210009 [2]中国生物技术发展中心,北京100039

出　　处：《生物加工过程》2011年第6期39-44,共6页Chinese Journal of Bioprocess Engineering

基　　金：国家自然科学基金资助项目(20906051);江苏省自然科学基金资助项目(BK2009478)

摘　　要：为提高目标产物异山梨醇的产率,考察多种固体酸催化剂催化山梨醇脱水的反应性能。结果表明:催化剂酸性与其催化性能之间有密切联系,酸性较强的H3PO4/Nb2O5催化剂显示出比其他催化剂更优异的催化性能。对磷酸负载量进行优化后,在n(P)/n(Nb)为0.8的H3PO4/Nb2O5催化剂上得到了100%的山梨醇转化率和63%的异山梨醇选择性。Dehydration of sorbitol to isosorbide on various solid acids was investigated to improve isosorbide yield.The results showed that the catalytic performances of solid acids were closely related to their acidities.H3PO4/Nb2O5 catalyst with stronger acidity showed better catalytic performance than other solid acids.The 100% sorbitol conversion and 63% isosorbide selectivity was obtained on H3PO4/Nb2O5 catalyst with n（P）/n（Nb）=0.8.

关 键 词：催化 异山梨醇 固体酸 山梨醇 

分 类 号：Q815[生物学—生物工程]