抗抑郁单味中药研究进展  

Research Progress of Traditional Chinese Medicines in Single Use as Antidepressants

作　　者：周王谊[1] 李欣欣[1] 

机构地区：[1]天津天士力研究院药理毒理所,天津300410

出　　处：《医学综述》2011年第23期3624-3627,共4页Medical Recapitulate

摘　　要：抑郁症在全球疾病覆盖中位居第四位,为多发病。在我国抑郁症的治疗中,西药处于主导地位,由于长期服用此类药物会出现严重的不良反应,许多患者常常被迫停止治疗。因此,从天然药物和中药方剂中寻找和研制理想的抗抑郁剂,愈来愈引起研究者的关注。近年来,国内外学者在中药领域进行的相关研究取得了可喜的进展,迄今为止发现的具有抗抑郁作用的单味中草药较多,部分草药已被开发。目前研究较多、较深入的单味中药是贯叶金丝桃,此外,大叶蒟、郁金、柴胡、石菖蒲、积雪草等数十味中药亦被证实有抗抑郁作用。Depression is a frequently-occurring disease,with a number four position in the global disease coverage.In the treatment of depression in China,western medicine is in a dominant position,which is often forced to be suspended as long-term use may have severe side effects.Therefore,more and more concerns have been generated to find and develop ideal antidepressants from the natural medicines and herbal prescriptions.In recent years,encouraging progress has been made in the TCM fields by researchers both in and outh of China,plenty of herbs in single use have been discovered to have antidepressant effect,some of which have already been developed.Currently the single herb with more and deeper research is Hypericum perforatum;besides,dozens of herbs such as large betel leaves,turmeric,bupleurum,acorus gramineus,and centella asiatica etc.have also been confirmed to have antidepressant effect.

关 键 词：抗抑郁症 中药 研究现状 

分 类 号：R971.43[医药卫生—药品]