田口试验设计法优化乳块消口服液微波提取工艺  

Optimization of Microwave Extraction Technology for Rukuaixiao Oral Liquid by Taguchi Experimental Design Method

作　　者：黄良勤[1] 周方勇 赵萍 骆科回 

机构地区：[1]遵义医学院,贵州遵义563000 [2]贵州三仁堂药业有限公司,贵州遵义563003 [3]绥阳县人民医院,贵州遵义563302

出　　处：《中国实验方剂学杂志》2011年第24期7-9,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：2011年度科技型中小企业技术创新基金(11C26115203625)

摘　　要：目的:采用田口试验设计法优选乳块消口服液微波提取工艺。方法:以橘叶有效成分橙皮苷为指标,以提取功率、提取时间、溶剂用量作为考察因素,采用L9(34)正交表设计试验,优化乳块消口服液药材提取工艺。结果:乳块消口服液药材最佳微波提取工艺为微波提取功率6 000 W,提取时间45 min,加水量6倍量,其指标成分橙皮苷与传统水煮提取工艺相比提高了80%,并且缩短了提取时间,加水量仅为原来的27.3%。结论:优选工艺节约了药材提取、浓缩工序能源消耗和时间。Objective：Taguchi experimental design method was used to optimize of microwave extraction process for Rukuaixiao oral liquid.Method：L9（34） orthogonal test was used to optimize extraction process of medicine from Rukuaixiao oral liquid with active ingredient in orange（hesperidin） as index.Investigation factors included extraction power,extraction time,the amount of solvent.Result：The best microwave extraction technology was as follows： microwave extraction power was 6 000 W,extracted 45 minutes with 6 times the amount of water,compared with traditional boiled extraction,extract ratio of hesperidin increased 80%,and extraction time was shorten,the amount of water was only 27.3% to original technology.Conclusion：Optimum technology saved energy and time of medicine extraction and concentration process.

关 键 词：乳块消 田口试验 微波提取 正交设计 

分 类 号：R283.6[医药卫生—中药学]